Related Experiment Video
Updated: Jul 25, 2025
06:15
Author Spotlight: Investigating the Key Factors of Obliterative Bronchiolitis After Lung Transplantation
Published on: November 10, 2023
933
Risk factors for recurrent wheezing after bronchiolitis.
Y H Fan1, P L Zhang1, Y J Huang2
1Department of Pediatric Pulmonary Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, 611731, China.
BMC Pediatrics
|June 23, 2023
Summary
Children hospitalized for bronchiolitis with a history of allergies, atopic dermatitis, allergic rhinitis, or family history of atopy are at higher risk for recurrent wheezing. Moraxella catarrhalis infection also plays a role.
Area of Science:
- Pediatrics
- Allergy and Immunology
- Respiratory Medicine
Background:
- Bronchiolitis is a common respiratory infection in infants.
- A subset of children who experience bronchiolitis develop recurrent wheezing.
- Identifying risk factors for recurrent wheezing is crucial for early intervention.
Purpose of the Study:
- To investigate the association between various factors and the development of recurrent wheezing in children after bronchiolitis.
- To identify independent risk factors for recurrent wheezing in this population.
Main Methods:
- A cohort of 167 children hospitalized for bronchiolitis was studied.
- Patients were categorized into recurrent wheezing (RWG) and non-recurrent wheezing (NRWG) groups.
- Statistical analyses, including t-tests, Mann-Whitney U-tests, chi-square tests, and logistic regression, were employed to compare risk factors.
Main Results:
- Children in the RWG had higher maternal age and a greater likelihood of allergic history, atopic dermatitis, allergic rhinitis, and atopic family history.
- Moraxella catarrhalis was more prevalent in the RWG.
- Atopic dermatitis, allergic rhinitis, and atopic family history were identified as independent risk factors for recurrent wheezing.
Conclusions:
- Allergic history, Moraxella catarrhalis infection, atopic dermatitis, allergic rhinitis, and atopic family history are associated with recurrent wheezing post-bronchiolitis.
- Atopic dermatitis, allergic rhinitis, and atopic family history are significant independent risk factors.
Related Concept Videos
01:29Asthma-I: Introduction
2.7K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
2.7K
01:17Pulmonary Cycle: Exhalation
1.6K
In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...
1.6K
01:26Asthma-II: Pathophysiology and Classification
2.7K
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
2.7K
01:20Asthma: Pathogenesis and Management
458
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
458
01:24Asthma-III: Symptoms and Complications
2.5K
Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
Classification of Asthma
2.5K
02:06Allergic Reactions
27.8K
Overview
27.8K