Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

The Resting Membrane Potential

The Resting Membrane Potential

Cardiac Action Potential

Cardiac Action Potential

Cardiac action potentials are essential for proper heart function, enabling the rhythmic contractions needed for adequate blood circulation. Nodal cells and Purkinje fibers, specialized for electrical conduction, generate these action potentials.
The cardiac action potential process involves a series of phases characterized by the movement of ions across the cardiac cell membranes, leading to the depolarization and repolarization of the cardiac myocytes.
Ionic Basis of Cardiac Action Potentials

Electrophysiology of Normal Cardiac Rhythm

Electrophysiology of Normal Cardiac Rhythm

The normal cardiac rhythm is a synchronized electrical activity that facilitates the regular and coordinated contraction of the heart muscle. This process is essential for efficient blood circulation throughout the body. The fundamental elements involved in establishing and maintaining this rhythm include the unique electrical properties of cardiac muscle cells, the sinoatrial (SA) node's pacemaker function, the specialized conducting system, and the ionic mechanisms underlying each phase...

Resting Membrane Potential

Resting Membrane Potential

The relative difference in electrical charge, or voltage, between the inside and the outside of a cell membrane, is called the membrane potential. It is generated by differences in permeability of the membrane to various ions and the concentrations of these ions across the membrane.
The Inside of a Neuron is More Negative
The membrane potential of a cell can be measured by inserting a microelectrode into a cell and comparing the charge to a reference electrode in the extracellular fluid. The...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Targeting Late Na<sup>+</sup> Current: Too Late or Better Late Than Never?

Circulation research·2026

Same author

Side-viewing probe for lesion depth mapping on the left ventricle epicardium with near-infrared spectroscopy.

Scientific reports·2026

Same author

Patient and arrest characteristics associated with rearrest and mortality following out of hospital cardiac arrest.

Resuscitation plus·2026

Same author

Multimodal PSOCT-NIRS catheter for guided ablation of atrial fibrillation.

Journal of biomedical optics·2026

Same author

Outcomes in Patients With Atrial Fibrillation Stratified by Body Mass Index and Heart Failure Status.

JACC. Advances·2026

Same author

A young man with stroke and right ventricular dysfunction.

HeartRhythm case reports·2024

Search research articles

Related Experiment Video

Updated: Jul 25, 2025

A Micro-agar Salt Bridge Electrode for Analyzing the Proton Turnover Rate of Recombinant Membrane Proteins

A Micro-agar Salt Bridge Electrode for Analyzing the Proton Turnover Rate of Recombinant Membrane Proteins

Published on: January 7, 2019

Can the E-Field Help Translate Repolarization From Bench to Bedside?

Kenneth R Laurita¹, Ohad Ziv¹

¹Heart and Vascular Research Center, MetroHealth Campus, Case Western Reserve University, Cleveland, Ohio, USA.

JACC. Clinical Electrophysiology

|June 24, 2023

Summary

No abstract available in PubMed .

Keywords:

electrogram heterogeneity repolarization

More Related Videos

Measuring the Induced Membrane Voltage with Di-8-ANEPPS

Measuring the Induced Membrane Voltage with Di-8-ANEPPS

Published on: November 19, 2009

A Galvanotaxis Assay for Analysis of Neural Precursor Cell Migration Kinetics in an Externally Applied Direct Current Electric Field

A Galvanotaxis Assay for Analysis of Neural Precursor Cell Migration Kinetics in an Externally Applied Direct Current Electric Field

Published on: October 13, 2012

Related Experiment Videos

Last Updated: Jul 25, 2025

A Micro-agar Salt Bridge Electrode for Analyzing the Proton Turnover Rate of Recombinant Membrane Proteins

A Micro-agar Salt Bridge Electrode for Analyzing the Proton Turnover Rate of Recombinant Membrane Proteins

Published on: January 7, 2019

Measuring the Induced Membrane Voltage with Di-8-ANEPPS

Measuring the Induced Membrane Voltage with Di-8-ANEPPS

Published on: November 19, 2009

A Galvanotaxis Assay for Analysis of Neural Precursor Cell Migration Kinetics in an Externally Applied Direct Current Electric Field

A Galvanotaxis Assay for Analysis of Neural Precursor Cell Migration Kinetics in an Externally Applied Direct Current Electric Field

Published on: October 13, 2012