Modulating covalent organic frameworks with accessible carboxyl to boost superior extraction of polar nitrobenzene
Suxin Zhou1, Yixin Kuang1, Hongkai Lin1
1Ministry of Education (MOE) Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-sen University, Guangzhou 510006, PR China.
Abstract:
The wide use and high polarity of nitrobenzene compounds (NBCs) have caused a concern for their residues in daily beverages. Herein, the covalent organic frameworks (COFs) with abundant carboxyl were ingeniously designed by introducing a novel modulator, and further developed as solid phase microextraction (SPME) coatings. Due to the enhanced polar interaction, the extraction efficiencies of modified COF for NBCs were sharply increased. After coupling the high-performance SPME fiber with gas chromatograph-mass spectrometry (GC-MS), an ultrasensitive analytical method was developed, with a wide linear range (0.50-5000 ng/L), and low limits of detection (0.15-3.0 ng/L). More importantly, the method was highly feasible and practical, leading to the precise determinations of trace NBCs from variously matrix-complicated samples. This work provides a viable and efficacious approach for the extraction and analysis of polar pollutants form complicated matrices, and is of great significance for mild COF modification and its extended applications in analytical chemistry.
Related Concept Videos
Extraction: Advanced Methods
Preparation of Carboxylic Acids: Hydrolysis of Nitriles
Electrophilic Aromatic Substitution: Nitration of Benzene
Preparation of Amines: Reduction of Oximes and Nitro Compounds
Though catalytic hydrogenation can reduce nitrobenzenes, the reduction is nonselective in the presence of other functional groups. For instance, if nitrobenzene contains an aldehyde group,...
Alcohols from Carbonyl Compounds: Reduction
Catalytic hydrogenation is similar to the reduction of an alkene or alkyne by adding H2 across the pi bond in the presence of transition metal catalysts like Raney Ni, Pd–C, Pt, or Ru. Aldehydes and ketones can be reduced by this method, often under mild to moderate heat (25–100°C) and...
Nitrosation of Enols


