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DIABETES MELLITUS AND COVID-19: TODAY'S CHALLENGES
L Markin1, T Fartushok1, N Fartushok2
11Department of Obstetrics & Gynecology Danylo Halytsky Lviv National Medical University, Ukraine.
Georgian Medical News
|June 24, 2023
Summary
Patients with diabetes face severe COVID-19 complications due to impaired immune response. This review analyzes literature for clinical recommendations for diabetes patients with COVID-19, focusing on pathogenesis and management.
Area of Science:
- Endocrinology and Infectious Diseases
- Immunology and Public Health
Background:
- Diabetes mellitus impairs immune responses, increasing susceptibility to infections like COVID-19.
- Hyperglycemia in diabetes compromises the immune system's ability to control pathogenic microorganisms, leading to worse outcomes.
Approach:
- Bibliometric analysis of literature databases (PubMed, SCOPUS, Web of Science, MedScape) from 2020-2022.
- Literature review focused on "diabetes and COVID-19" and related terms, including pathogenesis, clinical features, diagnosis, treatment, and recommendations.
- Analysis of studies involving middle-aged and elderly outpatients and inpatients (46-82 years) with diabetes and COVID-19, considering comorbidities.
Key Points:
- Identified 32 relevant publications on diabetes and COVID-19 between 2020 and 2022.
- Studies included diverse populations across France, China, USA, and Great Britain.
- Common comorbidities in patients with diabetes and COVID-19 included hypertension, cardiovascular diseases, and chronic kidney disease.
Conclusions:
- Highlights the critical need for understanding pathogenetic mechanisms linking diabetes and COVID-19.
- Emphasizes the importance of developing and disseminating clinical recommendations for managing patients with both conditions.
- Underscores the heightened risk and complexity of COVID-19 in individuals with diabetes.
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