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MOLECULAR EFFECTS OF RESVERATROL IN THE TREATMENT OF AUTOIMMUNE DISEASES
Yu Boldyreva1, E Zaharchuk2, I Lebedev3
11Department of Biological Chemistry, Tyumen State Medical University, Russian Federation.
Abstract:
The article represents the molecular effect of resveratrol on the course and progression of autoimmune processes. It has been shown that resveratrol in a low dose inhibits the formation and activity of some B-lymphocytes subpopulations. On the one hand, this leads to the use of resveratrol in the treatment of autoimmune diseases. On the other hand, it activates antitumor immunity. However, there are several problems that prevent the widespread use of resveratrol nowadays. In particular, its poor water solubility, bioavailability, and dosage. In order to place resveratrol as a cutting-edge molecule in medicine, additional multicenter and placebo-controlled trials have to be carried out.
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