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Updated: Jul 25, 2025

Early Pathological and Magnetic Resonance Detection of Cerebral Injury Using a Rat Model of Neonatal Hypoxic Ischemic Encephalopathy
Published on: October 28, 2022
Left Ventricular Function and Dimensions Are Altered Early in Infants Developing Brain Injury in the Setting of
Pierre Elias1, Anie Lapointe2, Pia Wintermark1
1Division of Neonatology, Montreal Children's Hospital, Montreal, QC, Canada; McGill University Health Centre - Research Institute, Montreal, QC, Canada.
Abstract:
We evaluated the association between left cardiac 3-dimensional echocardiographic parameters and brain injury in a single-center prospective study of neonates with neonatal encephalopathy. On day 2 of life, neonates with brain injury had greater left ventricle end-diastolic and stroke volume but also greater peak global circumferential strain detected by 3-dimensional echocardiogram.
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