Paediatric Adhesive Small Bowel Obstruction is Associated with a Substantial Economic Burden and High Frequency of

Cecilia Arana Håkanson1, Fanny Fredriksson2, Helene Engstrand Lilja3

  • 1Department of Women's and Children's Health, Karolinska Institutet, Tomtebodavägen 18a, 171 77, Solna, Sweden.

PubMed

Insights

Neonatal surgery frequently causes adhesive small bowel obstruction (ASBO) in children, often requiring surgery and leading to complications and high costs. Further research is needed for effective paediatric ASBO management guidelines.

Area of Science:

  • Pediatric Surgery
  • Gastroenterology
  • Surgical Complications

Background:

  • Intra-abdominal adhesions are a common cause of adhesive small bowel obstruction (ASBO), with a higher incidence in pediatric surgery.
  • Despite its prevalence, ASBO in children lacks clear management guidelines, and associated complications and economic burdens are not well-defined.

Purpose of the Study:

  • To investigate the underlying diagnoses, treatments, complications, and healthcare costs associated with pediatric ASBO.
  • To identify the primary drivers of ASBO in the pediatric population.

Main Methods:

  • An observational retrospective study of children aged 0-15 years hospitalized for ASBO between 2000 and 2020.
  • Data extraction from medical records, with complications classified using the Clavien-Dindo Classification.
  • Kaplan-Meier estimates were used for time-to-ASBO analysis.

Main Results:

  • 101 patients with 137 ASBO episodes were analyzed; 58.4% had initial surgery during the neonatal period.
  • Necrotizing enterocolitis, duodenal obstruction, and primary ASBO were the most common index surgery diagnoses.
  • Conservative treatment failed in 86.6% of patients, necessitating laparotomy; 52% experienced postoperative complications, with a median cost of $36,236 per ASBO episode.

Conclusions:

  • Neonatal surgery is a primary cause of pediatric ASBO, frequently requiring surgical intervention.
  • Paediatric ASBO is associated with a high rate of postoperative complications and substantial healthcare expenditures.
  • Development of evidence-based management guidelines for pediatric ASBO is crucial.
Abstract

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