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Acute Kidney Injury and Mid-term Outcomes After Extra-Cardiac Fontan Conversion
Tatsuya Kunigo1,2, Risa Oikawa3, Minoru Nomura3
1Department of Anesthesiology, Sapporo Medical University, School of Medicine, 291 South 1 West 16, Chuo-Ku, Sapporo-Shi, Hokkaido, 060-8543, Japan. tatsuya_9250@yahoo.co.jp.
Abstract:
The aim of this study was to investigate the association of postoperative acute kidney injury and unplanned re-admission rate due to heart failure at 2 years follow-up in patients who had extra-cardiac Fontan conversion. This was a retrospective single-center study of patients who underwent conversion from classic Fontan to extra-cardiac Fontan between January 2014 and December 2021. Acute kidney injury was defined using the Kidney Disease Improving Global Outcomes criteria. A total of 47 patients underwent Fontan conversion. Acute kidney injury occurred in 22 patients (46.8%) and 5 patients with acute kidney injury needed renal replacement therapy. Unplanned re-admission rate at 2-year follow-up was significantly higher in patients with acute kidney injury even when renal function returned to baseline (8 [36.4%] vs. 3 [12.0%], p = 0.026 by the log-rank test). In conclusion, postoperative acute kidney injury after extra-cardiac Fontan conversion was associated with unplanned re-admission due to heart failure at 2-year follow-up even though renal function was recovered.
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