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Circadian rhythm in cardiovascular diseases: a bibliometric analysis of the past, present, and future
Ruoning Chai1, Zelin Ye1, Qian Wu1
1Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Insights
Circadian rhythms significantly impact cardiovascular diseases (CVD). Research highlights inflammation, atherosclerosis, and myocardial infarction as key areas, with chronotherapy showing clinical potential.
Area of Science:
- Biomedical Sciences
- Chronobiology
- Cardiovascular Research
Background:
- Circadian rhythms regulate physiological processes crucial for health.
- Understanding circadian rhythm's role in cardiovascular diseases (CVD) is vital for health management.
- Bibliometric analysis offers insights into research trends in this field.
Purpose of the Study:
- To conduct a bibliometric analysis of research on circadian rhythm and CVD.
- To identify quantitative and qualitative trends, research hotspots, and future directions.
- To provide a comprehensive overview of the scientific landscape.
Main Methods:
- Data sourced from the Web of Science Core Collection.
- Bibliometric and visualization tools including HistCite, CiteSpace, and VOSviewer were employed.
- Analysis covered publication trends, leading contributors, core journals, and citation metrics.
Main Results:
- 2102 papers published, with a consistent year-on-year increase.
- The United States led in research output and citations.
- Key research areas evolved from hormones to inflammation, atherosclerosis, and myocardial infarction.
Conclusions:
- Circadian rhythm in CVD is a rapidly growing research area.
- Inflammation, atherosclerosis, and myocardial infarction are critical investigation areas.
- Further clinical trials are needed to translate chronotherapy into practice.
Background:
One of the most prominent features of living organisms is their circadian rhythm, which governs a wide range of physiological processes and plays a critical role in maintaining optimal health and function in response to daily environmental changes. This work applied bibliometric analysis to explore quantitative and qualitative trends in circadian rhythm in cardiovascular diseases (CVD). It also aims to identify research hotspots and provide fresh suggestions for future research.
Methods:
The Web of Science Core Collection was used to search the data on circadian rhythm in CVD. HistCite, CiteSpace, and VOSviewer were used for bibliometric analysis and visualization. The analysis included the overall distribution of yearly outputs, top nations, active institutions and authors, core journals, co-cited references, and keywords. To assess the quality and efficacy of publications, the total global citation score (TGCS) and total local citation score (TLCS) were calculated.
Results:
There were 2102 papers found to be associated with the circadian rhythm in CVD, with the overall number of publications increasing year after year. The United States had the most research citations and was the most prolific country. Hermida RC, Young ME, and Ayala DE were the top three writers. The three most notable journals on the subject were Chronobiology International, Hypertension Research, and Hypertension. In the early years, the major emphasis of circadian rhythm in CVD was hormones. Inflammation, atherosclerosis, and myocardial infarction were the top developing research hotspots.
Conclusion:
Circadian rhythm in CVD has recently received a lot of interest from the medical field. These topics, namely inflammation, atherosclerosis, and myocardial infarction, are critical areas of investigation for understanding the role of circadian rhythm in CVD. Although they may not be future research priorities, they remain of significant importance. In addition, how to implement these chronotherapy theories in clinical practice will depend on additional clinical trials to get sufficient trustworthy clinical evidence.
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