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Published on: April 17, 2021
Post-COVID-19 Cardiovascular Sequelae and Myocarditis
Lakshmi Chakradhar Yarlagadda1, Debasish Ghosh2, Ullash Basak1
1Intern Doctor, GSL Medical College and General Hospital, Rajahmundry, Andhra Pradesh.
Insights
Post-COVID-19 cardiovascular issues, including myocarditis and myocardial infarctions, are significant public health concerns. This review details acute and chronic cardiac manifestations and management strategies for coronavirus disease 2019 (COVID-19).
Area of Science:
- Cardiology
- Infectious Diseases
- Public Health
Background:
- Cardiovascular (CV) complications, including myocarditis and myocardial infarctions (MIs), are significant public health issues following coronavirus disease 2019 (COVID-19).
- This review synthesizes current knowledge on acute and chronic cardiac manifestations associated with COVID-19.
Approach:
- A comprehensive literature search was conducted across multiple electronic databases from 2020 to 2022.
- Seventy-three articles detailing COVID-19 and its cardiac manifestations were identified and analyzed.
Key Points:
- Cardiometabolic risk factors play a crucial role in exacerbating COVID-19 severity.
- The review covers cardiac pathology, mechanisms of CV consequences in acute COVID-19, and microvascular injury.
- It also addresses chronic CV disease linked with COVID-19 and therapeutic drug effects on the heart.
Conclusions:
- Understanding the cardiac pathology and consequences of COVID-19 is vital for clinical practice.
- Investigational approaches and management strategies for post-COVID-19 cardiovascular sequelae are discussed.
- Prioritizing cardiometabolic risk factors is essential for managing COVID-19 patients.
Background And Aim:
Post coronavirus disease 2019 (COVID-19) cardiovascular (CV) pathological changes, myocarditis, and myocardial infarctions (MIs) are major public health issues. This review discusses acute and chronic COVID-19 cardiac manifestations.
Methods:
The devastating impact of COVID-19 on global healthcare and economies has likely been one of humanity's deadliest calamities in recent decades, as multiple literature and databases were searched from 2020 to 2022.
Results:
As of April 2022, we identified 73 articles in various electronic databases that discussed the details of COVID-19 and cardiac manifestations. Cardiometabolic risk factors should now, more than ever, be a top priority for clinicians, as their potent role in exacerbating COVID-19 illness severity has been conclusively demonstrated.
Conclusion:
This review discusses cardiac pathology changes, CV consequences of acute COVID-19, microvascular injury and cardiac complications linked with SARS-CoV2, COVID-19 linked with chronic CV disease, therapeutic drug effects on heart used in COVID-19, and possible investigational approaches and management strategies for post-COVID-19 CV consequences. Highlights Cardiac pathology changes: Effect of COVID-19. Mechanism of development of CV consequences in acute COVID-19: Including autopsy studies. Microvascular injury and cardiac complications: Linked with SARS-CoV2. COVID-19 linked with chronic CV disease. Therapeutic drug effects on heart used in COVID-19. Possible investigational approaches and management strategies for post-COVID-19 CV consequences.
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