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Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression
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Healthy sleep patterns and common mental disorders among individuals with cardiovascular disease: A prospective

Zhi Cao1, Yabing Hou2, Hongxi Yang3

  • 1School of Public Health, Hangzhou Normal University, Hangzhou, China; School of Public Health, Zhejiang University School of Medicine, Hangzhou, China; Hangzhou International Urbanology Research Center & Center for Urban Governance Studies, Hangzhou, China.

Journal of Affective Disorders
|June 25, 2023
PubMed

Insights

Improving sleep health may lower depression risk in cardiovascular disease (CVD) patients. A healthy sleep pattern significantly reduces the likelihood of developing depression, emphasizing sleep

Area of Science:

  • Cardiology
  • Psychiatry
  • Sleep Medicine

Background:

  • Sleep behaviors are recognized as modifiable risk factors for cardiovascular disease (CVD) and common mental disorders.
  • The interplay between combined sleep behaviors and mental health outcomes in individuals with pre-existing CVD is not well understood.

Purpose of the Study:

  • To investigate the association between combined sleep behaviors and the incidence of depression and anxiety in individuals with a history of CVD.
  • To determine if a healthy sleep pattern can mitigate the risk of developing common mental disorders in this population.

Main Methods:

  • Utilized UK Biobank data from 18,776 participants with CVD history, excluding those with prior depression or anxiety.
  • Developed a composite healthy sleep score based on chronotype, sleep duration, insomnia, snoring, and excessive daytime sleepiness.
  • Employed Cox proportional hazard regression models to assess the risk of incident depression and anxiety.

Main Results:

  • Over 11.8 years, a healthy sleep pattern was linked to a 55% lower risk of depression (HR=0.45) and a 23% lower risk of anxiety (HR=0.77) compared to a poor sleep pattern.
  • A significant linear dose-response relationship was observed, where each 1-point increase in the healthy sleep score reduced depression risk by 18% (HR=0.82) and anxiety risk by 8% (HR=0.92).
  • These findings were consistent across various cardiovascular conditions, including coronary heart disease, stroke, heart failure, and atrial fibrillation.

Conclusions:

  • A healthy sleep pattern is significantly associated with a reduced risk of depression among individuals with CVD.
  • Monitoring and improving sleep health are crucial for preventing common mental disorders in patients with cardiovascular disease.
Abstract

Keywords:
AnxietyCardiovascular diseaseDepressionSleep patternUK Biobank

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