[A case of retroperitoneal alveolar soft part sarcoma]

Area of Science:

• Oncology
• Surgical Pathology
• Medical Imaging

Background:

• Alveolar soft part sarcoma (ASPS) is a rare soft tissue malignancy with a predilection for young adults.
• Retroperitoneal ASPS is exceptionally uncommon, with limited case reports globally.
• This study documents the initial presentation and management of retroperitoneal ASPS in Japan.

Observation:

• A 27-year-old woman presented with a retroperitoneal tumor.
• Initial surgical resection was followed by bilateral lung metastasectomy.
• Recurrence of the retroperitoneal tumor occurred despite initial treatment.

Findings:

• The recurrent retroperitoneal tumor was unresectable.
• Intra-arterial chemotherapy with cisplatin and adriamycin was administered.
• Radiotherapy was also employed as part of the treatment strategy.
• The patient demonstrated resistance to both chemotherapy and radiotherapy.

Implications:

• This case highlights the aggressive nature and treatment challenges of retroperitoneal ASPS.
• Limited treatment options exist for unresectable and recurrent ASPS.
• Further research into novel therapeutic strategies for advanced ASPS is warranted.
• This case contributes to the understanding of ASPS management in a Japanese population.