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Updated: Jul 25, 2025

An Anaerobic Biosensor Assay for the Detection of Mercury and Cadmium
Published on: December 17, 2018
Thiol-grafted covalent organic framework-based electrochemical platforms for sensitive detection of Hg(II) ions
Xiang Tang1, Qingqing Zhang1, Dongyang Chen2
1Hunan Provincial Key Laboratory of Micro & Nano Materials Interface Science, College of Chemistry and Chemical Engineering, Central South University, Changsha, Hunan 410083, China. reynard.tangjuntao@gmail.com.
Abstract:
Triazine-based covalent organic frameworks functionalized by thiol and thioether (COFS-CH/COFS-SH) were designed and served as a platform that could bind with mercury ions specifically based on Hard-Soft-Acid-Base theory. As such, when employing COFs as a modifier in a carbon paste electrode (CPE), the COFS-CH-modified CPE revealed an extraordinary performance (detection limit of 0.01 ppb; linear range of 0.1 to 1.0 ppb) and repeatability for electrochemical detection of trace mercury, even in real samples collected from tap or lake water. This innovative approach leverages the inherent properties of covalent organic frameworks (COFs) to enable highly sensitive and selective detection of target analytes.
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