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Published on: July 12, 2024
Effectiveness of Timely Implementation of Palliative Care on the Well-Being of Patients With Chronic Heart Failure: A
Lu Pan1, Li Qiao2, Yuzhe Zhang3
1Department of Geriatrics, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China.
Insights
Palliative care (PC) significantly improves quality of life and cardiac function in chronic heart failure (HF) patients, especially those with NYHA class II or III. Early PC intervention is beneficial for NYHA class II patients.
Area of Science:
- Cardiology
- Palliative Care
Background:
- Lack of consensus on timely palliative care (PC) implementation for chronic heart failure (HF).
- Need to determine optimal timing for PC intervention in HF patients across different cardiac function classes.
Purpose of the Study:
- Investigate the impact of primary PC intervention on chronic HF patients.
- Identify the proper time point for implementing primary PC intervention based on cardiac function.
Main Methods:
- 180 chronic HF patients (NYHA class I-III) were randomized into usual care (UC) or PC intervention groups.
- Evaluated quality of life (QoL), left ventricular ejection fraction, and N-terminal pro-B-type natriuretic peptide over 24 weeks.
Main Results:
- PC intervention group showed significantly improved QoL and cardiac function compared to UC.
- NYHA class II and III patients in the PC group experienced significant improvements.
- No significant difference was observed in NYHA class I patients between groups.
Conclusions:
- Palliative care programs effectively enhance QoL and cardiac function in chronic HF.
- Evidence supports timely PC referral for NYHA class II patients for optimal benefit.
Abstract:
Objectives: To date, there is a lack of consensus on the timely implementation of palliative care (PC) in patients with chronic heart failure (HF). We aimed to investigate the impact of primary PC intervention on chronic HF patients with different classes of cardiac function, and to determine a proper time point for the implementation of primary PC intervention. Methods: A consecutive series of 180 chronic HF patients with the New York Heart Association (NYHA) Cardiac function ranging from I to III were enrolled in this study. Patients with the same cardiac function class, they were randomized and equally assigned to the usual care (UC) group or to the PC intervention group. At the end of 24-week treatment, quality-of-life (QoL) measurements were evaluated. Left ventricular ejection fraction and N-terminal pro-B-type natriuretic peptide were measured for each group at baseline and the final follow-up, respectively. Results: Through the 6-month follow-up, patients randomized to the PC intervention group presented significantly better QoL and cardiac function as compared with patients randomized to the UC group alone. Subgroup analysis showed that for patients with NYHA class II or III, significantly improved cardiac function and QoL were observed in the PC intervention group as compared with the control group. As for patients with class I, no significant difference was found between the 2 groups. Conclusions: Palliative program can effectively improve the QoL and cardiac function of patients with chronic HF. Moreover, we provided evidence on timely referral of patients to PC intervention, which could be beneficial for patients with NYHA class II.
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