Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Lattice Centering and Coordination Number02:33

Lattice Centering and Coordination Number

9.7K
The structure of a crystalline solid, whether a metal or not, is best described by considering its simplest repeating unit, which is referred to as its unit cell. The unit cell consists of lattice points that represent the locations of atoms or ions. The entire structure then consists of this unit cell repeating in three dimensions. The three different types of unit cells present in the cubic lattice are illustrated in Figure 1.
Types of Unit Cells
Imagine taking a large number of identical...
9.7K
Trends in Lattice Energy: Ion Size and Charge02:54

Trends in Lattice Energy: Ion Size and Charge

24.0K
An ionic compound is stable because of the electrostatic attraction between its positive and negative ions. The lattice energy of a compound is a measure of the strength of this attraction. The lattice energy (ΔHlattice) of an ionic compound is defined as the energy required to separate one mole of the solid into its component gaseous ions. For the ionic solid sodium chloride, the lattice energy is the enthalpy change of the process:
24.0K
Bewley Lattice Diagram01:12

Bewley Lattice Diagram

771
The Bewley lattice diagram, developed by L. V. Bewley, effectively organizes the reflections occurring during transmission-line transients. It visually represents how voltage waves propagate and reflect within a transmission line, making it easier to understand the complex interactions that occur.
771
Structures of Solids02:22

Structures of Solids

14.3K
Solids in which the atoms, ions, or molecules are arranged in a definite repeating pattern are known as crystalline solids. Metals and ionic compounds typically form ordered, crystalline solids. A crystalline solid has a precise melting temperature because each atom or molecule of the same type is held in place with the same forces or energy. Amorphous solids or non-crystalline solids (or, sometimes, glasses) which lack an ordered internal structure and are randomly arranged. Substances that...
14.3K
Long-term Potentiation01:25

Long-term Potentiation

2.8K
Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
Hebbian LTP
LTP can occur when...
2.8K
Metallic Solids02:37

Metallic Solids

18.5K
Metallic solids such as crystals of copper, aluminum, and iron are formed by metal atoms. The structure of metallic crystals is often described as a uniform distribution of atomic nuclei within a “sea” of delocalized electrons. The atoms within such a metallic solid are held together by a unique force known as metallic bonding that gives rise to many useful and varied bulk properties.
All metallic solids exhibit high thermal and electrical conductivity, metallic luster, and malleability....
18.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

<i>In Vitro</i> Activities of Bedaquiline and Delamanid against Nontuberculous Mycobacteria Isolated in Beijing, China.

Antimicrobial agents and chemotherapy·2019
Same author

Para-aminosalicylic acid increases the susceptibility to isoniazid in clinical isolates of <i>Mycobacterium tuberculosis</i>.

Infection and drug resistance·2019
Same author

Virulence, Molecular Diversity, and Mating Type of <i>Curvularia lunata</i> in China.

Plant disease·2019
Same author

Effect of solution chemistry and aggregation on adsorption of perfluorooctanesulphonate (PFOS) to nano-sized alumina.

Environmental pollution (Barking, Essex : 1987)·2019
Same author

Angle-Independent Structurally Colored PS@TiO<sub>2</sub> Film with Excellent Underwater Superoleophobicity in Harsh Environments.

Langmuir : the ACS journal of surfaces and colloids·2019
Same author

Developmental transcriptomics of Chinese cordyceps reveals gene regulatory network and expression profiles of sexual development-related genes.

BMC genomics·2019
Same journal

Correction to "On the shape of the radiation survival curve in tumor spheroids: The role of oxygen heterogeneity".

Medical physics·2026
Same journal

Multi-view constrained semi-supervised vertebra detection for 3D ultrasound spine volume.

Medical physics·2026
Same journal

Accuracy of quantitative <sup>177</sup>Lu SPECT/CT imaging: A systematic review.

Medical physics·2026
Same journal

Physics-constrained dual-domain network for CBCT reconstruction from orthogonal X-rays in gynecologic radiotherapy.

Medical physics·2026
Same journal

Decomposition-based harmonization for quantitative PET imaging across scanners and radiotracers.

Medical physics·2026
Same journal

Development and evaluation of an in vivo dose-based monitoring system for electron FLASH radiation therapy.

Medical physics·2026
See all related articles

Related Experiment Video

Updated: Jul 25, 2025

Stable DNA Motifs, 1D and 2D Nanostructures Constructed from Small Circular DNA Molecules
09:32

Stable DNA Motifs, 1D and 2D Nanostructures Constructed from Small Circular DNA Molecules

Published on: April 12, 2019

6.5K

Lattice position optimization for LATTICE therapy.

Weijie Zhang1, Yuting Lin1, Fen Wang1

  • 1Department of Radiation Oncology, University of Kansas Medical Center, Lawrence, Kansas, USA.

Medical Physics
|June 26, 2023
PubMed
Summary
This summary is machine-generated.

This study introduces a novel LATTICE radiation therapy planning method that optimizes lattice vertex positions. This approach improves tumor dose coverage and spares organs-at-risk (OAR) for better patient outcomes.

Keywords:
IMPTIMRTLATTICE/GRID radiation therapypeak-to-valley dose ratio (PVDR)spatially fractionated radiotherapy (SFRT)

More Related Videos

Indirect Fabrication of Lattice Metals with Thin Sections Using Centrifugal Casting
08:32

Indirect Fabrication of Lattice Metals with Thin Sections Using Centrifugal Casting

Published on: May 14, 2016

12.6K
Visualizing Surface T-Cell Receptor Dynamics Four-Dimensionally Using Lattice Light-Sheet Microscopy
09:24

Visualizing Surface T-Cell Receptor Dynamics Four-Dimensionally Using Lattice Light-Sheet Microscopy

Published on: January 30, 2020

8.1K

Related Experiment Videos

Last Updated: Jul 25, 2025

Stable DNA Motifs, 1D and 2D Nanostructures Constructed from Small Circular DNA Molecules
09:32

Stable DNA Motifs, 1D and 2D Nanostructures Constructed from Small Circular DNA Molecules

Published on: April 12, 2019

6.5K
Indirect Fabrication of Lattice Metals with Thin Sections Using Centrifugal Casting
08:32

Indirect Fabrication of Lattice Metals with Thin Sections Using Centrifugal Casting

Published on: May 14, 2016

12.6K
Visualizing Surface T-Cell Receptor Dynamics Four-Dimensionally Using Lattice Light-Sheet Microscopy
09:24

Visualizing Surface T-Cell Receptor Dynamics Four-Dimensionally Using Lattice Light-Sheet Microscopy

Published on: January 30, 2020

8.1K

Area of Science:

  • Radiation Oncology
  • Medical Physics
  • Computational Biology

Background:

  • LATTICE radiation therapy delivers heterogeneous doses with high peak-to-valley dose ratios (PVDR) to tumors.
  • Current LATTICE planning fixes vertex positions, limiting optimization of PVDR and organ-at-risk (OAR) sparing.

Purpose of the Study:

  • To develop and validate a new LATTICE treatment planning method optimizing lattice vertex positions.
  • This is the first study to optimize lattice positions in LATTICE radiation therapy planning.

Main Methods:

  • The novel method jointly optimizes lattice vertex positions and plan variables (e.g., photon fluences, proton spot weights).
  • Lattice vertices are approximated using sigmoid functions for differentiability and constrained for geometric feasibility.
  • Iterative convex relaxation (ICR) and ADMM solve the optimization problem, with joint updates via the Quasi-Newton method.

Main Results:

  • The new LATTICE method successfully identified optimal lattice vertex positions, validated against exhaustive search ground truth.
  • Achieved superior results in terms of reduced optimization objective, increased target PVDR, and enhanced OAR sparing compared to standard methods.
  • Demonstrated effectiveness for both photon and proton LATTICE radiation therapy.

Conclusions:

  • A new LATTICE treatment planning method optimizing vertex positions is proposed and validated.
  • This method enhances target PVDR and OAR sparing by optimizing both lattice positions and plan variables.
  • Represents a significant advancement in LATTICE radiation therapy planning for improved clinical efficacy.