Related Experiment Video

Updated: Aug 18, 2026

The Unpredictable Chronic Mild Stress Protocol for Inducing Anhedonia in Mice
07:13

The Unpredictable Chronic Mild Stress Protocol for Inducing Anhedonia in Mice

Published on: October 24, 2018

[Mechanisms of the development of the terminal state in experimental emotional stress]

L S Ul'ianinskiĭ, I L Kosharskaia, Iu G Starinskiĭ

    Kardiologiia
    |May 1, 1986
    PubMed

    More Related Videos

    A Chronic Immobilization Stress Protocol for Inducing Depression-Like Behavior in Mice05:28

    A Chronic Immobilization Stress Protocol for Inducing Depression-Like Behavior in Mice

    Published on: May 15, 2019

    Restraint to Induce Stress in Mice and Rats03:48

    Restraint to Induce Stress in Mice and Rats

    Published on: December 6, 2024

    Related Concept Videos

    Physiology of Emotion01:20

    Physiology of Emotion

    The physiology of emotions is a multifaceted process involving the autonomic nervous system, brain structures, hormones, and neurotransmitters. This intricate interplay dictates how emotions manifest in the body and influence behavior.
    Autonomic Nervous System
    The autonomic nervous system (ANS) plays a critical role in emotional responses by regulating involuntary physiological functions. It consists of two main components: the sympathetic and parasympathetic systems. The sympathetic system...
    Introduction to Stress and Lifestyle01:27

    Introduction to Stress and Lifestyle

    Stress is a multifaceted response to events perceived as challenging or threatening, highlighting physical, emotional, cognitive, and behavioral reactions. Physically, stress can lead to fatigue, sleep disruptions, and various health issues such as frequent colds, chest pains, and nausea. Emotionally, it can manifest as anxiety, depression, irritability, and anger triggered by both minor and major life events. Cognitively, it may result in difficulty in concentration, memory, and...
    Psychological Responses to Stress01:20

    Psychological Responses to Stress

    Psychological responses to stress encompass the various cognitive and emotional reactions individuals experience when faced with challenging or threatening situations, such as a job loss. Prolonged exposure to stressors can disturb emotional balance, increasing negative emotions (e.g., anxiety and sadness) and diminishing positive emotions (e.g., joy and satisfaction). These persistent emotional shifts are associated with an increased risk of both physical illness and mental health issues, such...
    Physiological Foundation of Stress01:24

    Physiological Foundation of Stress

    Stress triggers a coordinated physiological response involving the sympathetic nervous system (SNS) and the hypothalamic-pituitary-adrenal (HPA) axis. This dual activation ensures that the body is prepared for both immediate and prolonged stress management. The process begins with the perception of a stressor. This initial phase activates the SNS, leading to the rapid release of adrenaline (epinephrine) from the adrenal glands.
    Role of the Sympathetic Nervous System
    Adrenaline triggers the...
    Lazarus's Cognitive Appraisal Theory01:20

    Lazarus's Cognitive Appraisal Theory

    Cognitive psychologist Richard Lazarus proposed the cognitive-mediational theory of emotions, which emphasizes how individuals' assessments of stressors significantly affect their experience of stress. According to Lazarus, the stress response is determined by a two-step appraisal process: primary appraisal and secondary appraisal. These cognitive appraisals help individuals evaluate the potential impact of a stressor and determine the adequacy of their coping resources.
    Primary Appraisal:...
    Stress and Mental Health01:30

    Stress and Mental Health

    Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
    Individuals with depression often experience challenges in both their personal and professional...