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Vesiculobullous eosinophilic annular erythema: A case report
Madeleine Lachance1, Sheila Vallée1, Éric Gagné2
1Department of Dermatology, CHU de Québec-Université Laval, Québec, QC, Canada.
SAGE Open Medical Case Reports
|June 26, 2023
Summary
Eosinophilic annular erythema, a rare skin condition, can present with blisters. This case showed a rare vesiculobullous form that responded well to dapsone treatment.
Area of Science:
- Dermatology
- Immunology
Background:
- Eosinophilic annular erythema (EAE) is a rare eosinophilic dermatosis.
- Characterized by arcuate erythematous urticarial plaques of unclear etiology.
- Vesiculobullous forms of EAE are exceptionally rare.
Observation:
- This report details a rare vesiculobullous form of EAE.
- The patient presented with extensive cutaneous involvement.
- The condition was poorly responsive to prednisone treatment.
Findings:
- Complete remission was achieved with dapsone therapy.
- Dapsone demonstrated significant efficacy in this rare presentation.
- This highlights dapsone as a potential treatment option.
Implications:
- This case expands the understanding of EAE presentations.
- It suggests dapsone as a viable therapeutic strategy for refractory vesiculobullous EAE.
- Further research into EAE pathogenesis and treatment is warranted.

