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Updated: Jul 25, 2025

An Integrated Approach for Microprotein Identification and Sequence Analysis
Published on: July 12, 2022
IsoAnalytics: a single-cell proteomics web server
Suzette N Palmer1,2,3, Andrew Y Koh1,4,5, Xiaowei Zhan3,5
1Division of Hematology/Oncology, Department of Pediatrics, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Motivation:
Single-cell proteomics provide unprecedented resolution to examine biological processes. Customized data analysis and facile data visualization are crucial for scientific discovery. Further, user-friendly data analysis and visualization software that is easily accessible for the general scientific community is essential.
Results:
We have created a web server, IsoAnalytics, that gives users without computational or bioinformatics background the ability to directly analyze and interactively visualize data obtained from the Isoplexis single cell technology platform. We envision this open-sourced web server will increase research productivity and serve as a free, competitive alternative for single-cell proteomics research.
Availability And Implementation:
IsoAnalytics is free and available at: https://cdc.biohpc.swmed.edu/isoplexis/ and is implemented in Python, with all major browsers supported. Code for IsoAnalytics is free and available at: https://github.com/zhanxw/Isoplexis_Data_Analysis.
Supplementary Information:
Supplementary data are available at Bioinformatics Advances online.
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