Related Experiment Videos
From science to business: translating live biotherapeutic products to the clinic
1Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain.
Nature Reviews Bioengineering
|June 26, 2023
Abstract:
At Pulmobiotics, we engineer bacteria for the treatment of respiratory diseases. Here, we outline how we designed MycoChassis - an attenuated bacterium strain obtained by genome engineering of Mycoplasma pneumoniae (a human lung pathogen) - and discuss the challenges on the road to its clinical translation.