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Pulmonary hypertension (PH) is a severe health condition in which the mean pulmonary arterial pressure increases to 25 mmHg or more, even when the body is at rest. This high pressure in the blood vessels that transport blood from the heart to the lungs can cause various symptoms, including shortness of breath, can lead to right heart failure, and significantly affect the overall quality of life.
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Artificial intelligence applied in pulmonary hypertension: a bibliometric analysis.

Germaine Tchuente Foguem1, Aurelien Teguede Keleko2

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Summary

This study uses bibliometric analysis to map how artificial intelligence is being used in pulmonary hypertension research, identifying key trends, top-performing institutions, and major scientific themes to guide future clinical and technical development.

Keywords:
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Area of Science:

  • Medical informatics research involving Artificial Intelligence applications
  • Cardiopulmonary medicine and clinical diagnostics

Background:

No prior work had resolved the full scope of computational advancements regarding complex cardiopulmonary conditions. That uncertainty drove interest in how modern algorithms might improve patient outcomes. It was already known that managing multi-organ pathologies presents significant challenges for clinical practitioners. This gap motivated a comprehensive look at current literature trends. Prior research has shown that early identification of such illnesses remains a primary goal for healthcare systems. Scholars have increasingly turned to automated systems to handle growing datasets. However, the integration of these tools into standard practice requires a clear understanding of existing research patterns. This study addresses the need to synthesize the current state of technological integration in this specific medical domain.

Purpose Of The Study:

The aim is to provide a systematic review through a quantitative analysis of the scientific production concerning this complex condition. This study addresses the need to understand recent developments in computational approaches applied to clinical practice. The researchers seek to map the networks of scientific production to identify key contributors. They intend to evaluate research performance using various standardized indicators and statistical methods. This work aims to clarify the main scientific issues and challenges currently facing the field. By assessing these factors, the authors hope to highlight both the progress made and the limits observed. The study provides a guideline for practitioners to navigate the evolution of these technologies. Ultimately, the motivation is to promote the wide dissemination of knowledge regarding digital health applications.

Main Methods:

Review Approach involved a systematic quantitative evaluation of existing academic publications. The authors utilized statistical methods to process large volumes of citation data. Data mining techniques were applied to extract relevant information from major scholarly databases. The team performed network analysis to visualize connections between different research entities. They assessed performance using standardized metrics of scientific production and impact. This methodology allowed for the identification of key trends across the global literature. The researchers carefully filtered the collected records to ensure high data quality. Finally, they synthesized these findings to provide a clear overview of the current intellectual landscape.

Main Results:

Key Findings From the Literature show a diverse range of high-impact journals leading the field. IEEE Access and Computers in Biology and Medicine are among the top-tier publications identified. The analysis highlights that universities in the United States and the United Kingdom dominate the current research output. Prominent institutions include Harvard Medical School and Imperial College London. The most frequently cited terms in the literature are Classification, Diagnosis, Disease, Prediction, and Risk. These results demonstrate a strong emphasis on predictive and diagnostic modeling. The data indicate that institutional collaboration is a major driver of scientific progress. These findings provide a baseline for understanding the current trajectory of digital health research.

Conclusions:

The authors suggest that this quantitative mapping serves as a roadmap for future investigations into automated diagnostic tools. They propose that identifying top-tier journals helps researchers target their dissemination efforts more effectively. The findings imply that global institutional collaborations are driving the current pace of innovation. Synthesis and Implications reveal that understanding these publication networks clarifies the limitations of existing models. The researchers note that ethical data handling remains a priority throughout the lifecycle of these computational projects. They argue that this overview assists practitioners in navigating the rapidly evolving landscape of machine learning. The authors conclude that such analyses promote wider awareness of both breakthroughs and persistent gaps in the field. This work provides a structured framework for evaluating the impact of digital health initiatives on patient care.

The researchers propose that machine learning models improve the accuracy of patient stratification. By analyzing large datasets, these systems identify patterns that assist in the early detection of vascular resistance, unlike traditional manual screening methods which often overlook subtle physiological changes.

The authors utilize the Web of Science Core Collection and Google Scholar as their primary databases. These platforms provide the necessary citation metrics to evaluate research performance, contrasting with smaller, specialized repositories that may lack the breadth required for global bibliometric mapping.

The researchers state that the inclusion of diverse journals, such as IEEE Access and Frontiers in Cardiovascular Medicine, is necessary to capture the interdisciplinary nature of the field. This breadth ensures that both engineering-focused and clinical-centric advancements are represented in the final dataset.

The authors employ bibliometric indicators to quantify scientific impact and production volume. These data types allow for the objective assessment of institutional contributions, distinguishing between high-output research centers and emerging academic groups that are just beginning to influence the field.

The study measures the frequency of terms like Classification, Diagnosis, and Prediction within the literature. These metrics reveal that the focus of current research is shifting toward predictive modeling, whereas earlier studies concentrated primarily on basic disease characterization and descriptive clinical reporting.

The researchers propose that this analysis increases the visibility of current progress and limitations. By highlighting these factors, the study assists practitioners in understanding the evolution of digital activities, which helps bridge the gap between technical development and clinical implementation.