Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pharmacovigilance01:19

Pharmacovigilance

908
Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
908
Drug Control Governance: Regulatory Bodies and Their Impact01:03

Drug Control Governance: Regulatory Bodies and Their Impact

191
Drug control governance involves the oversight and regulation of pharmaceuticals to ensure their safety and efficacy while preventing illegal drug use and trafficking. Regulatory bodies, including the US Food and Drug Administration (FDA) and the European Union's European Medicines Agency (EMA), play a central role in this process. These agencies evaluate the safety and efficacy of drugs before they can be marketed. They fund clinical trials and assess the benefits and risks associated with...
191
Drug Regulation01:25

Drug Regulation

1.4K
Drug regulation encompasses the management of drug usage by evaluating its safety and efficacy through assessments conducted by regulatory authorities. Regrettably, the history of drug regulation is marred by several catastrophic events. One such incident is the Elixir Sulfanilamide tragedy, in which the toxic compound diethyl glycol was included in a sweet-tasting medication, leading to numerous fatalities. This event prompted the enactment of the Food, Drug, and Cosmetic Act in 1938. Under...
1.4K
Drug Distribution: Overview01:11

Drug Distribution: Overview

237
Drug distribution within the body is a dynamic process involving the movement of a drug in two directions across various compartments: from the bloodstream into tissues (tissue uptake) and from tissues back into the bloodstream (tissue release or redistribution). This process is passive and primarily driven by two variables: the concentration gradient between the bloodstream and the extravascular tissues and the drug's ability to cross the cell membrane.
Initially, the free drug in the...
237
Principles of Disease Surveillance01:26

Principles of Disease Surveillance

131
Disease surveillance is the systematic collection, analysis, and interpretation of health data essential to the planning, implementation, and evaluation of public health practice. This process integrates data dissemination to entities responsible for preventing and controlling disease, injury, and disability. Surveillance systems provide crucial information for action, helping public health authorities make informed decisions to manage and prevent outbreaks, ensure public safety, optimize...
131
Pharmacokinetics: Overview01:10

Pharmacokinetics: Overview

6.6K
Pharmacokinetics is a scientific discipline that focuses on the journey of a drug within the body, encompassing four key stages: absorption, distribution, metabolism, and elimination. The first stage, absorption, involves the drug's transfer into the bloodstream. Several factors dictate the extent and speed of this process. For example, the liver often metabolizes oral drugs before they reach systemic circulation, leading to only partial absorption. In contrast, intravenous (IV)...
6.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Bridging the gap in tuberculosis care: A mixed-methods analysis of patient safety challenges and solutions in India.

The Indian journal of tuberculosis·2026
Same author

Health-related quality of life and its predictors in cancer patients with antimicrobial-resistant infections: A prospective study.

Infection, disease & health·2026
Same author

Disproportionality analysis of semaglutide-associated bile-duct cancer: A vigibase study.

Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology·2026
Same author

Discovery of uranium content in breastmilk and assessment of associated health risks for mothers and infants in Bihar, India.

Scientific reports·2025
Same author

Discovering metabolic pathways associated with immune activation in people living with HIV following ChAdOx1 nCoV-19 vaccination using mass spectrometry.

Journal of pharmaceutical and biomedical analysis·2025
Same author

How did the COVID-19 pandemic impact post-marketing safety studies?

Expert opinion on drug safety·2025

Related Experiment Video

Updated: Jul 25, 2025

Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model
23:56

Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model

Published on: October 31, 2010

16.8K

Pharmacovigilance in the Caribbean Countries: an Overview.

Kingsley E W Walker1, Reshma Bankay1, Satish Jankie2

  • 1Department of Paraclinical Sciences, The University of the West Indies, St. Augustine, Trinidad and Tobago.

Current Pharmacology Reports
|June 26, 2023
PubMed
Summary

Caribbean pharmacovigilance (PV) systems require significant enhancement to meet WHO standards. Increased online drug access and falsified medicines necessitate improved post-marketing surveillance and adverse drug reaction (ADR) reporting across the region.

Keywords:
Adverse drug reaction reportingCaribbean countriesPharmaceutical policiesPharmacovigilanceRegulatory framework and legislationWest Indies

More Related Videos

An Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited Settings
19:57

An Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited Settings

Published on: March 30, 2014

18.6K
High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry
10:17

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry

Published on: April 23, 2019

9.7K

Related Experiment Videos

Last Updated: Jul 25, 2025

Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model
23:56

Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model

Published on: October 31, 2010

16.8K
An Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited Settings
19:57

An Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited Settings

Published on: March 30, 2014

18.6K
High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry
10:17

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry

Published on: April 23, 2019

9.7K

Area of Science:

  • Pharmaceutical Sciences
  • Public Health
  • Regulatory Affairs

Background:

  • The COVID-19 pandemic exacerbated drug shortages and increased online access to medicines.
  • E-commerce platforms facilitate the widespread marketing of substandard and falsified pharmaceuticals.
  • Compromised drug quality necessitates enhanced post-marketing surveillance in the pharmaceutical industry.

Purpose of the Study:

  • To evaluate Caribbean pharmacovigilance (PV) systems against WHO minimum requirements.
  • To underscore the critical role of PV in ensuring medicine safety in the Caribbean.
  • To identify challenges and opportunities for developing robust PV systems in the region.

Main Methods:

  • Comparative analysis of national PV systems in selected Caribbean countries.
  • Assessment of adherence to WHO pharmacovigilance guidelines.
  • Review of existing regulatory frameworks and reporting mechanisms for adverse drug reactions (ADRs).

Main Results:

  • Caribbean PV systems largely do not meet WHO minimum requirements.
  • Adverse drug reaction (ADR) reporting is minimal due to low awareness and participation.
  • Few Caribbean nations actively participate in the WHO global PV network.

Conclusions:

  • Sustainable PV systems in the Caribbean require legislative and regulatory improvements.
  • Enhanced political commitment, funding, and reporting incentives are crucial.
  • Building comprehensive PV systems is essential for safeguarding public health in the region.