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Water structure modification by d-(+)-glucose at different concentrations and temperatures-effect of mutarotation
Mohammad Hossain1, Noortaz Chowdhury1, Amiya Atahar1
1Department of Chemistry, University of Dhaka Dhaka 1000 Bangladesh.
RSC Advances
|June 26, 2023
Summary
d-(+)-glucose alters water structure by affecting hydrogen bonding, influencing viscosity and density. This study reveals insights into glucose-water interactions and the mutarotation mechanism.
Area of Science:
- Physical Chemistry
- Biophysical Chemistry
- Solution Chemistry
Background:
- Carbohydrate-water interactions are crucial in chemical and biological systems.
- Understanding glucose's effect on water structure is fundamental.
- Molecular-level insights into these interactions are needed.
Purpose of the Study:
- To investigate how d-(+)-glucose modifies water structure.
- To explore the thermodynamic and structural changes induced by glucose.
- To elucidate the mechanism of glucose mutarotation in water.
Main Methods:
- Thermodynamic analysis (density, viscosity, refractive index).
- Dynamic Light Scattering (DLS) for aggregate size.
- Polarimetry and Near-Infrared (NIR) spectroscopy for mutarotation kinetics and water structure.
- Difference spectroscopy and 2D correlation spectroscopy (2DCOS).
Main Results:
- Glucose alters water structure, impacting viscosity and density.
- NIR spectroscopy showed enhanced hydrogen bond cleavage in water.
- Refractive index indicated increased free water concentration over time.
- Evidence suggests multiple water molecules participate in mutarotation.
Conclusions:
- Glucose influences water's hydrogen-bonding network.
- A concerted mechanism for proton transfer in mutarotation is proposed.
- These findings enhance fundamental knowledge of carbohydrate-water systems.
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