Related Experiment Video
Updated: Jul 25, 2025

Intratibial Osteosarcoma Cell Injection to Generate Orthotopic Osteosarcoma and Lung Metastasis Mouse Models
Published on: October 28, 2021
Paratesticular Osteosarcoma-A Rare Tumor with Distinctive Imaging Findings
Lesin Kumar Nithiyanandham1, Indhuja Muthiah Vaikundaraja2, Shirley Sundersingh3
1Department of Surgical Oncology, Cancer Institute, Chennai, Tamil Nadu, India.
Abstract:
Extraosseous osteosarcoma (EOO) is a rare mesenchymal malignancy representing 4% of all osteosarcomas and 1% of soft tissue sarcomas. The testes, its supporting structures, that is, paratestes, and the spermatic cord are among the rarest sites for EOO, with only 11 published English language reports to date. We report our experience with a 73-year-old male presenting with left hemiscrotal swelling, noted to have extensive amorphous intratumoral calcification on imaging. He underwent left high inguinal orchidectomy with en bloc hemiscrotectomy, with a final pathologic diagnosis of primary paratesticular osteosarcoma. Our literature review corroborates this distinctive, hitherto overlooked imaging feature.

