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Updated: Jul 25, 2025
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COVID-19 Immune Response In Adults Post Measles-Rubella Vaccination.
Suwoyo Suwoyo1, Erna Rahma Yani1, Koekoeh Hardjito1
1Health Polytechnic, Ministry of Health, Malang, East Java, Indonesia.
Abstract:
Objective: This study aimed to see how measles, mumps, and rubella vaccination affected the increase in SARS-CoV-2 immunoglobulin levels in individuals who had received the second dose of the SARS-CoV-2 vaccine. Material and Method: This research is a quasi-experimental type with a pre-post test design. The population studied were adults who had received the second dose of the SARS-CoV-2 vaccine, consisting of 30 people. Results: The results of this study were that most (60%) research subjects experienced an increase in IgM and some subjects (46.6%) experienced an increase in anti-SARS-CoV-2 IgG levels. The administration of the MR vaccination had no effect on increasing anti-SARS-CoV-2 IgG and IgM levels. This happened because the increase in IgM and IgG levels in the pre and post-tests in most research subjects was relatively low. Conclusion: The administration of the MR vaccine to adults who had received a second dose of the SARS-CoV-2 vaccine elicited a response with low levels of IgG and IgM SARS-CoV-2.
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