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Prediction of in-hospital mortality rate in COVID-19 patients with diabetes mellitus using machine learning methods
Pooneh Khodabakhsh1, Ali Asadnia2, Alieyeh Sarabandi Moghaddam3
1Department of IT and Computer Engineering, Azad Islamic University South Tehran Branch, Tehran, Iran.
Insights
COVID-19 significantly impacts diabetic patients. This study identified age (51-80), CPR, and ICU stay as key factors influencing the discharge status of hospitalized diabetic COVID-19 patients.
Area of Science:
- Medical Informatics
- Epidemiology
- Public Health
Background:
- Coronavirus 2019 (COVID-19) has caused a global health crisis, with millions infected and deceased worldwide.
- Identifying and predicting COVID-19 outcomes is a critical healthcare priority.
- Diabetic patients represent a significant at-risk population for adverse COVID-19 outcomes.
Purpose of the Study:
- To analyze COVID-19 patient data, focusing on those with diabetes.
- To identify key factors influencing the clinical course and discharge status of diabetic COVID-19 patients.
- To develop a predictive model for patient release status using a decision tree algorithm.
Main Methods:
- Utilized a dataset of 29,817 COVID-19 patients hospitalized between October 2019 and March 2021.
- Focused analysis on 2,824 diabetic COVID-19 patients.
- Employed a decision tree algorithm for data analysis, association rule mining, and prediction of patient release status.
Main Results:
- The decision tree model achieved 87.07% accuracy, 88% sensitivity, and 80% specificity in predicting patient release status.
- Association rules were mined to understand patient characteristics and outcomes.
- Identified age category (51-80), CPR, and ICU residency as pivotal factors in discharge status for diabetic inpatients.
Conclusions:
- Diabetic patients constitute the largest group of at-risk individuals among hospitalized COVID-19 patients.
- Age, CPR, and ICU residency are crucial determinants for the discharge status of diabetic COVID-19 inpatients.
- The study highlights the importance of considering these factors in managing diabetic patients with COVID-19.
Background:
Since its emergence in December 2019, until June 2022, coronavirus 2019 (COVID-19) has impacted populations all around the globe with it having been contracted by ~ 535 M people and leaving ~ 6.31 M dead. This makes identifying and predicating COVID-19 an important healthcare priority.
Method And Material:
The dataset used in this study was obtained from Shahid Beheshti University of Medical Sciences in Tehran, and includes the information of 29,817 COVID-19 patients who were hospitalized between October 8, 2019 and March 8, 2021. As diabetes has been shown to be a significant factor for poor outcome, we have focused on COVID-19 patients with diabetes, leaving us with 2824 records.
Results:
The data has been analyzed using a decision tree algorithm and several association rules were mined. Said decision tree was also used in order to predict the release status of patients. We have used accuracy (87.07%), sensitivity (88%), and specificity (80%) as assessment metrics for our model.
Conclusion:
Initially, this study provided information about the percentages of admitted Covid-19 patients with various underlying disease. It was observed that diabetic patients were the largest population at risk. As such, based on the rules derived from our dataset, we found that age category (51-80), CPR and ICU residency play a pivotal role in the discharge status of diabetic inpatients.
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