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Updated: Jul 26, 2026

Measuring Post-Stroke Cerebral Edema, Infarct Zone and Blood-Brain Barrier Breakdown in a Single Set of Rodent Brain Samples
Published on: October 23, 2020
, , MODIFIED ASSESSMENT OF NEUROLOGICAL AND NEUROPSYCHOLOGICAL DEFICIT IN PATIENTS WITH CHRONIC CEREBRAL ISCHEMIA AND
Tatiana V Chernii1, Volodymyr I Cherniy1, Daria О Fokina1
1STATE INSTITUTION OF SCIENCE «RESEARCH AND PRACTICAL CENTRE OF PREVENTIVE AND CLINICAL MEDICINE» STATE ADMINISTRATIVE DEPARTMENT, KYIV, UKRAINE.
Objective:
The aim: To develop and test the scale of the modified assessment of neurological and neuropsychological deficits (MANND), which would include data on neurological status, higher cortical function disorders, and emotional disorders.
Patients And Methods:
Materials and methods: A clinical-neurological and neuropsychological examination was carried out based on the data of a fragment of a scientific study - a comprehensive study: "Improving patient-oriented approaches to the treatment of patients with cardiovascular and cerebrovascular diseases and comorbid conditions."
Results:
Results: The Modified Assessment of Neurological and Neuropsychological Deficits is a neurological symptom assessment scale designed specifically for patients with chronic cerebral ischemia. It takes into account quantitative changes in the neurological status, namely, damage to the pyramidal, sensory, extrapyramidal, coordinating systems, damage to the cranial nerves, and the most common neurological syndromes, such as cephalic, asthenic, and higher cortical function disorders. This scale is a sensitive comprehensive method for assessing the severity of neurological and neuropsychological deficits, in contrast to existing scales for the isolated assessment of focal neurological symptoms (motor deficits, cognitive disorders or disorders of the emotional sphere).
Conclusion:
Conclusions: The modified assessment of neurological and neuropsychological deficits can be recommended both for use in clinical practice and for conducting scientific research, as a unique quantitative scale developed taking into account all the features of a wide spectrum of neurological pathology in patients with chronic brain ischemia.
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