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Updated: Jul 25, 2025

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Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models
Published on: March 1, 2015
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Dysphagia screening post-stroke: systematic review.
Stefano Mancin1,2,3, Marco Sguanci4, Francesco Reggiani2,5
1Nutrition Unit, Cancer Center, IRCCS Humanitas Research Hospital, via Manzoni, 56 20089 Rozzano, Italy.
BMJ Supportive & Palliative Care
|June 26, 2023
Summary
Dysphagia screening is crucial for chronic stroke patients. The Volume-Viscosity Swallow Test shows high accuracy for identifying swallowing difficulties and aspiration risk in post-stroke individuals.
Area of Science:
- Neurology
- Clinical Medicine
- Swallowing Disorders
Background:
- Stroke is a leading cause of mortality, often complicated by dysphagia (swallowing difficulties).
- Effective assessment of nutritional status and aspiration risk is vital for improving clinical outcomes in stroke survivors.
- Identifying suitable dysphagia screening tools for chronic post-stroke patients is essential for timely intervention.
Approach:
- A systematic literature search was performed across major databases (Cochrane, PubMed, Embase, CINAHL, Scopus, Web of Science) from 2000 to 2022.
- Manual searches of reference lists and Google Scholar supplemented the database search to ensure comprehensive data retrieval.
- Two independent reviewers conducted article screening, selection, inclusion, and quality/bias assessment.
Key Points:
- Ten studies, primarily cross-sectional (n=9), involving 1653 chronic post-stroke patients were included.
- The Volume-Viscosity Swallow Test was the only tool used in multiple studies with sufficient sample size.
- This test demonstrated high diagnostic accuracy (sensitivity: 96.6%-88.2%; specificity: 83.3%-71.4%) when compared to videofluoroscopic swallowing studies.
Conclusions:
- Dysphagia is a significant complication in chronic stroke patients, necessitating early identification.
- Screening tools with proven diagnostic accuracy are paramount for effective management.
- Limitations include a limited number of available studies and small sample sizes, highlighting the need for further research.

