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Updated: Jul 25, 2025

A Reproducible Cartilage Impact Model to Generate Post-Traumatic Osteoarthritis in the Rabbit
Published on: November 21, 2023
Unraveling the mechanisms behind joint damage
Wenyu Fu1,2, Chuan-Ju Liu1,2
1Department of Orthopaedic Surgery, New York University Grossman School, New York, United States.
A specific type of myeloid monocyte drives the progression from autoimmunity to joint damage in rheumatoid arthritis. This finding offers new insights into rheumatoid arthritis pathogenesis.
Area of Science:
- Immunology
- Rheumatology
- Cell Biology
Background:
- Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by joint inflammation and destruction.
- The precise cellular mechanisms driving the transition from systemic autoimmunity to localized joint pathology in RA remain incompletely understood.
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