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Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced...
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Scurvy: Rediscovering a Forgotten Disease.

Mustafa Gandhi1, Omar Elfeky2, Hamza Ertugrul3

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Summary

Scurvy, a vitamin C deficiency, causes diverse symptoms affecting connective tissues. Though rare, it still affects malnourished individuals and can be treated with vitamin C supplementation.

Keywords:
gastrointestinal bleedingmucosal oozescurvyvitamin C deficiencyvitamin C supplementation

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Area of Science:

  • Nutrition
  • Biochemistry
  • Pathology

Background:

  • Scurvy is a historical nutritional deficiency disease resulting from inadequate vitamin C intake.
  • Vitamin C is crucial for collagen synthesis and connective tissue integrity.
  • While rare in modern times, scurvy persists, particularly in vulnerable populations.

Purpose of the Study:

  • To review the clinical manifestations, risk factors, and management of scurvy.
  • To highlight scurvy as an unusual cause of gastrointestinal bleeding.
  • To emphasize the importance of vitamin C in preventing and treating scurvy.

Main Methods:

  • Literature review of scurvy cases and relevant biochemical pathways.
  • Analysis of clinical presentations including dermatological, musculoskeletal, and gastrointestinal symptoms.
  • Examination of risk factors such as malnutrition, alcoholism, and socioeconomic status.

Main Results:

  • Scurvy presents with varied symptoms affecting multiple organ systems, including bleeding gums, joint pain, skin lesions, and poor wound healing.
  • Gastrointestinal bleeding is an uncommon but significant manifestation of scurvy.
  • Elderly, malnourished individuals, and those with poor dietary habits are at higher risk.

Conclusions:

  • Scurvy, though infrequent, remains a relevant diagnosis, especially in specific demographic groups.
  • Prompt diagnosis and treatment with vitamin C supplementation are effective in managing scurvy.
  • Public health awareness regarding adequate vitamin C intake is essential for prevention.