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Effect of Cryogenic Treatment on Low-Density Magnesium Multicomponent Alloys with Exceptional Ductility.

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Biocorrosion and Cytotoxicity Studies on Biodegradable Mg-Based Multicomponent Alloys.

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Numerical Investigation on Precipitation Hardening of Mg-Gd Alloys.

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Correction: Kuc et al. Tension-Dominant Orthodontic Loading and Buccal Periodontal Phenotype Preservation: An Integrative Mechanobiological Model Supported by FEM and a Proof-of-Concept CBCT. <i>J. Funct. Biomater.</i> 2026, <i>17</i>, 47.

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Updated: Jun 19, 2026

Multi-Scale Modification of Metallic Implants With Pore Gradients, Polyelectrolytes and Their Indirect Monitoring In vivo
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Magnesium-Based Temporary Implants: Potential, Current Status, Applications, and Challenges.

Sankaranarayanan Seetharaman1,2, Dhivya Sankaranarayanan1, Manoj Gupta1

  • 1Department of Mechanical Engineering, College of Design and Engineering, National University of Singapore, 9 Engineering Drive 1, Block EA #07-08, Singapore 117575, Singapore.

Journal of Functional Biomaterials
|June 27, 2023
PubMed
Summary
This summary is machine-generated.

Magnesium-based materials show promise as temporary biomedical implants due to their strength and biocompatibility. This review summarizes their properties, applications, and fabrication methods for successful implantation.

Keywords:
applicationsbiocompatiblebiodegradableclinical trialscommercial implantsdegradation behaviorimplantsmagnesium alloys

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Area of Science:

  • Biomaterials Science
  • Medical Engineering
  • Materials Science

Background:

  • Biomedical implants are crucial for tissue/organ repair and replacement.
  • Implant success relies on material properties like mechanical strength, biocompatibility, and biodegradability.
  • Traditional implants face challenges, driving the search for advanced materials.

Purpose of the Study:

  • To provide a comprehensive review of magnesium (Mg)-based materials for temporary biomedical implants.
  • To summarize the mechanical properties, biocompatibility, biodegradability, and bioactivity of Mg-based materials.
  • To discuss findings from in-vitro, in-vivo, and clinical studies, along with fabrication methods and applications.

Main Methods:

  • Literature review of current research on Mg-based materials for implants.
  • Analysis of studies focusing on mechanical, biocompatible, biodegradable, and bioactive properties.
  • Compilation of data from in-vitro, in-vivo, and clinical trials.

Main Results:

  • Magnesium-based materials exhibit excellent strength, biocompatibility, biodegradability, and bioactivity.
  • These properties make them highly suitable for temporary biomedical implant applications.
  • Research indicates positive outcomes in in-vitro, in-vivo, and clinical settings.

Conclusions:

  • Magnesium-based materials are a promising candidate for next-generation temporary biomedical implants.
  • Their tunable properties and degradation profiles offer significant advantages over conventional materials.
  • Further research and development in fabrication techniques will enhance their clinical translation.