A Highly Selective Schiff Base Based Chemodosimeter for the Detection of Perfluorooctanoic Acid by Optical Biosensor
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Published on: November 20, 2013
Sathya Vijayakumar1, Lavanya Raja1, Srinivasadesikan Venkatesan2
1Department of Organic Chemistry, School of Chemistry, Madurai Kamaraj University, Madurai, Tamilnadu, 625021, India.
Abstract:
A simple imine derivative based sensor (IDP) has been synthesized and characterized by 1 H NMR, 13 C NMR and mass spectral techniques. IDP is more capable of detecting perfluorooctanoic acid (PFOA) in a selective and sensitive manner. The PFOA as a biomarker interacts with IDP and shows "TURN-ON" response by colorimetric and fluorimetric method. Under optimized experimental observations, the selective determination of PFOA using IDP among other competitors as biomolecules has been noticed. The detection limit is 0.31 × 10- 8 mol/L. The practical applications of the IDP is effectively evaluated in human biofluids and water samples.

