Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hypothalamic self-stimulation in cats exposed to a hyperbaric environment.

G K Ankmetova, E L Polyakov, G V Troshikhin

    Neuroscience and Behavioral Physiology
    |January 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    [Age-development changes of the sympathetic innervation of the rat stomach.]

    Advances in gerontology = Uspekhi gerontologii·2019
    Same author

    The delayed effect of cortagen on the restoration of injured nerve function.

    Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections·2002
    Same author

    [Compensatory reactions of the rabbit respiratory system to hypoxic stimulation in hyperbaric conditions].

    Aviakosmicheskaia i ekologicheskaia meditsina = Aerospace and environmental medicine·1996
    Same author

    [The characteristics of the reaction of the rabbit respiratory system to CO2 under hyperbaric conditions].

    Fiziologicheskii zhurnal imeni I.M. Sechenova·1993
    Same author

    [Changes in the content of rat brain polyphosphoinositides after exposure to high partial pressures of helium and nitrogen].

    Ukrainskii biokhimicheskii zhurnal (1978)·1992
    Same author

    [The effect of different gas mixtures under increased pressure on the self-stimulation reaction of rabbits].

    Fiziologicheskii zhurnal·1992

    High pressure nitrogen exposure initially increased hypothalamic self-stimulation frequency in cats. Subsequent exposures showed adaptation, suggesting nitrogen narcosis at elevated pressures.

    Area of Science:

    • Neuroscience
    • Hyperbaric Medicine
    • Animal Behavior

    Background:

    • Investigating the neurological effects of hyperbaric environments is crucial for understanding physiological responses to extreme conditions.
    • The impact of elevated partial pressures of inert gases, like nitrogen, on central nervous system function requires further elucidation.

    Purpose of the Study:

    • To quantify changes in hypothalamic self-stimulation frequency in cats exposed to high-pressure nitrogen-oxygen environments.
    • To explore the adaptive responses and potential mechanisms underlying these behavioral changes.

    Main Methods:

    • Cats were exposed to a nitrogen-oxygen environment at 6 kg/cm² pressure.
    • Hypothalamic self-stimulation frequency was measured during initial and subsequent exposures.

    Related Experiment Videos

  • Behavioral responses were monitored during and after decompression.

    • Main Results:

    • An initial 200-300% increase in self-stimulation frequency was observed during the first exposure.
    • Decompression led to a temporary depression of the reaction, followed by normalization by the third day.
    • A second exposure indicated adaptation to the elevated partial pressure of nitrogen.

    Conclusions:

    • Changes in self-stimulation frequency are likely linked to the narcotic effects of nitrogen at elevated pressures.
    • The observed adaptation suggests the feline nervous system can adjust to prolonged hyperbaric nitrogen exposure.
    • Further research is warranted to fully understand the neurophysiological underpinnings of nitrogen narcosis.