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Development and Characterization of Fusidic Acid-Loaded Alginate-Aloe vera Based Hydrogel FilmWound Healing
Published on: December 13, 2024
646
Recent update on alginate based promising transdermal drug delivery systems
Sreejan Manna1, Prajna Gupta2, Gouranga Nandi2
1Department of Pharmaceutical Technology, Brainware University, Kolkata, West Bengal, India.
Journal of Biomaterials Science. Polymer Edition
|June 27, 2023
Summary
Alginates, derived from marine sources, are increasingly used in transdermal drug delivery systems (TDDS) due to their favorable properties. This review explores alginate applications in advanced TDDS technologies.
Area of Science:
- Biomaterials Science
- Pharmaceutical Sciences
- Drug Delivery
Background:
- Transdermal drug delivery systems (TDDS) offer an alternative to oral administration, gaining patient acceptance.
- Novel TDDS techniques include microneedle patches, films, and hydrogels.
- Natural polysaccharides are attractive for TDDS due to their hydrogel-forming and rheological properties.
Purpose of the Study:
- To review the source and properties of alginates.
- To explore various transdermal delivery techniques.
- To summarize the application of alginates in different transdermal systems.
Main Methods:
- Literature review focusing on alginate properties and TDDS.
- Analysis of alginate's suitability for hydrogel formulations.
- Examination of alginate's role in microneedle patches and films.
Main Results:
- Alginates are marine-derived anionic polysaccharides with excellent biodegradability, biocompatibility, and mucoadhesive properties.
- These properties make alginates highly suitable for TDDS applications.
- Alginates are being increasingly integrated into various advanced transdermal technologies.
Conclusions:
- Alginates are versatile biomaterials for developing effective transdermal drug delivery systems.
- Their unique properties support their use in innovative TDDS like hydrogels and microneedle patches.
- The application of alginates in TDDS is a growing area in pharmaceutical research.
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