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Association of Hypertension, Diabetes, and Cardiovascular Disease with COVID-19 in Africa: Scoping Review Protocol
Faisal Nooh1,2,3,4, Jürg Utzinger1,2, Daniel H Paris1,2
1Swiss Tropical and Public Health Institute, Kreuzstrasse 2, CH-4123 Allschwil, Switzerland.
Insights
This scoping review examines COVID-19 severity in African patients with noncommunicable diseases (NCDs). Findings will inform management strategies for hypertension, diabetes, and cardiovascular diseases during pandemics.
Area of Science:
- Public Health
- Epidemiology
- Infectious Diseases
Background:
- COVID-19 significantly impacted global healthcare, with higher mortality in the elderly and those with chronic conditions.
- Limited data exists on the association between COVID-19 severity and noncommunicable diseases (NCDs) in African populations.
Purpose of the Study:
- To estimate COVID-19 severity in African patients diagnosed with hypertension, diabetes, and cardiovascular diseases (CVDs).
- To explore the implications of these associations for effective case management strategies.
Main Methods:
- A scoping review adhering to PRISMA-ScR guidelines.
- Comprehensive literature search across major databases (PubMed, Scopus, Web of Science, Embase, CINAHL, JBI).
- Data extraction by two reviewers for articles published post-March 2020, followed by descriptive and narrative synthesis.
Main Results:
- The review is expected to quantify the increased risk of severe COVID-19 among patients with pre-existing NCDs.
- Identification of key trends and data gaps regarding NCDs and COVID-19 severity in Africa.
Conclusions:
- This review will establish an evidence base to guide recommendations for surveillance systems and referral guidelines.
- Findings will support improved management of NCDs during COVID-19 and future pandemics in African healthcare settings.
Background:
COVID-19 caused devastating effects on global healthcare systems. The elderly and people with chronic comorbidities were at a particularly high risk of mortality and morbidity. However, the evidence on the association of COVID-19 severity with noncommunicable diseases (NCDs) in the African population is scarce.
Objective:
The aim is to estimate COVID-19 severity among African patients with hypertension, diabetes, and cardiovascular diseases (CVDs) and its implications for case management.
Methods:
We will adhere to the extension for Scoping Reviews of PRISMA (PRISMA-ScR). The following electronic databases will be searched: PubMed, Scopus, Web of Science, Embase, CINAHL, and Joanna Briggs Institute. The search will be conducted after the publication of this protocol. Two reviewers will extract data from articles published after March 2020 without language restrictions. A descriptive analysis of the important findings and a narrative synthesis of the results will serve as the basis for interpretation. Expected results and conclusions: This scoping review is expected to determine the odds of patients with chronic comorbidities to progress to severe stages of COVID-19. The review will generate an evidence-based and set foundation for recommendations toward the establishment of surveillance systems and referral guidelines for the management of NCDs in the face of COVID-19 and future pandemics.
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