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Related Concept Videos

Diabetes: Symptoms, Diagnosis, and Complications01:15

Diabetes: Symptoms, Diagnosis, and Complications

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For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
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Pathophysiology of Diabetes01:20

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Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
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Diabetes Mellitus: Overview and Type I Subtype01:22

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Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
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Diabetes: Management and Pharmacotherapy01:15

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The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
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Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
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The Bittersweet Beat: Diabetes Complications.

Joana Rossell1,2,3, Marina Idalia Rojo-López1,3, Josep Julve1,2,3

  • 1Institut d'Investigació Biomèdica de l'Hospital de la Santa Creu i Sant Pau (IIB-Sant Pau), 08041 Barcelona, Spain.

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Summary

This editorial reviews recent research on cardiometabolic complications in diabetes mellitus. It highlights key findings and future directions in managing these serious health issues.

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Area of Science:

  • Cardiology
  • Endocrinology
  • Metabolic Diseases

Background:

  • Diabetes mellitus is a global health concern associated with numerous cardiometabolic complications.
  • These complications significantly increase morbidity and mortality in diabetic patients.
  • Recent research focuses on understanding and mitigating these risks.

Discussion:

  • The editorial synthesizes findings from recent publications in the Journal of Clinical Medicine.
  • It covers diverse aspects of cardiometabolic complications, including pathophysiology, diagnosis, and treatment.
  • Emphasis is placed on the interdisciplinary nature of managing these conditions.

Key Insights:

  • Early identification and intervention are crucial for managing cardiometabolic risk in diabetes.
  • Personalized treatment strategies are essential due to the heterogeneity of patient responses.
  • Novel therapeutic targets are emerging for both diabetes and its cardiovascular sequelae.

Outlook:

  • Future research should explore innovative approaches to prevent and treat diabetes-related heart and metabolic issues.
  • Continued investigation into the interplay between metabolic dysregulation and cardiovascular health is warranted.
  • Translational research is key to improving clinical outcomes for patients with diabetes mellitus.