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Biopolymer-Based Nanogel Approach in Drug Delivery: Basic Concept and Current Developments.
Ebru Altuntaş1, Burcu Özkan2, Sevgi Güngör1
1Faculty of Pharmacy, Department of Pharmaceutical Technology, Istanbul University, 34116 Istanbul, Türkiye.
Pharmaceutics
|June 28, 2023
Summary
Nanogels, versatile polymer-based nanoparticles, offer enhanced drug delivery and biomedical applications due to their tunable properties. This review details their design, methods, and recent advancements in therapeutic and diagnostic uses.
Area of Science:
- Polymer Science
- Biomedical Engineering
- Materials Science
Background:
- Nanogels, derived from natural and synthetic polymers, exhibit high surface area, swelling capacity, and drug-loading potential.
- Their tunable properties, including non-toxicity, biocompatibility, and biodegradability, make them ideal for biomedical applications.
Purpose of the Study:
- To review the design and application methodologies of nanogels.
- To discuss recent advancements in nanogel biomedical applications, focusing on drug and biomolecule delivery.
Main Methods:
- Literature review of nanogel synthesis and characterization techniques.
- Analysis of current research on nanogel applications in drug delivery, tissue engineering, and bioimaging.
Main Results:
- Nanogels provide a flexible platform for customized micro/nano carrier development.
- Significant progress has been made in utilizing nanogels for targeted drug delivery and enhanced therapeutic efficacy.
Conclusions:
- Nanogels represent a promising class of materials for advanced biomedical applications.
- Further research into nanogel design and application will continue to drive innovation in medicine and biotechnology.
