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Related Concept Videos

Drug Delivery: Miscellaneous Routes01:22

Drug Delivery: Miscellaneous Routes

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Drug delivery methods like oral inhalation, nasal sprays, transdermal patches, eye drops, intravitreal injection,  and rectal administration provide localized effects with reduced toxicity.
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...
403
Drug Delivery: Overview01:16

Drug Delivery: Overview

327
The selection of a drug's delivery route depends upon its physicochemical properties, including lipid or water solubility and ionization, as well as the therapeutic requirement, such as immediate or sustained effect. These routes can be divided into three primary categories: enteral, parenteral, and topical.
Enteral delivery involves administering drugs directly through swallowing, sublingual placement, or buccal application. Orally administered drugs predominantly navigate the...
327
Drug Delivery: Enteral Route01:18

Drug Delivery: Enteral Route

522
The enteral drug administration involves three primary routes: oral, sublingual, and buccal. Oral ingestion is the most prevalent, safe, economical, and convenient method for drug administration. However, it has certain drawbacks, including limited absorption due to the drug's low water solubility or poor membrane permeability, possible emesis from GI mucosa irritation, destruction of drugs by digestive enzymes or low gastric pH, and irregular absorption along with food or other drugs.
522
Routes of Drug Administration: Overview01:22

Routes of Drug Administration: Overview

6.4K
Drug administration involves delivering drugs to the body through various routes, such as enteral, parenteral, and topical.
Enteral administration refers to drugs absorbed through the gastrointestinal tract. They can be swallowed (perorally), placed under the tongue (sublingually), or on the inner lining of the cheeks (buccally). Perorally administered drugs take time to be absorbed and have a slower onset of action. The rectal route is another form of enteral administration, which allows for...
6.4K
Additional Routes of Drug Administration01:18

Additional Routes of Drug Administration

2.9K
Choosing the appropriate route of drug administration is significantly influenced by two key factors: the therapeutic objectives and the inherent properties of the drug being used.
Administering drugs via inhalation allows for the direct delivery of gaseous, volatile substances or droplets to different parts of the respiratory tract. One of the advantages of the inhalation route is the rapid absorption of drugs into the circulatory system, which is possible because of the large surface area of...
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Drug Delivery: Parenteral Route01:29

Drug Delivery: Parenteral Route

642
The parenteral route is a critical method of drug administration. It delivers compounds directly into the systemic circulation and bypasses the gastrointestinal tract. This approach is particularly advantageous for drugs that exhibit poor absorption or instability when administered orally.
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...
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Alternating Magnetic Field-Responsive Hybrid Gelatin Microgels for Controlled Drug Release
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Topical Drug Delivery: Innovative Controlled Release Systems.

Daniele Ribeiro de Araujo1,2, Cristina Padula3

  • 1Human and Natural Sciences Center, ABC Federal University, Santo Andre 09210-580, SP, Brazil.

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Innovative drug delivery systems are crucial for administering bioactive molecules effectively. This research focuses on designing advanced systems to improve therapeutic outcomes.

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Area of Science:

  • Biomaterials Science
  • Nanotechnology
  • Pharmacology

Background:

  • Effective administration of bioactive molecules is essential for therapeutic success.
  • Traditional drug delivery methods often face challenges like poor bioavailability and targeted delivery.
  • Advanced drug delivery systems offer innovative solutions to overcome these limitations.

Discussion:

  • The study explores novel strategies for designing drug delivery systems.
  • Emphasis is placed on optimizing the release kinetics and targeting capabilities.
  • The potential of these systems to enhance therapeutic efficacy is investigated.

Key Insights:

  • Development of sophisticated drug delivery platforms.
  • Improved stability and controlled release of bioactive agents.
  • Enhanced therapeutic outcomes through targeted delivery.

Outlook:

  • Future research will focus on clinical translation and large-scale production.
  • Exploration of new bioactive molecules for these advanced systems.
  • Potential for personalized medicine approaches using tailored drug delivery.