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An Overview of Indian Biomedical Research on the Chikungunya Virus with Particular Reference to Its Vaccine, an Unmet

Muhammed Muhsin Varikkodan1, Faisal Kunnathodi2, Sarfuddin Azmi2

  • 1Department of Bioscience Technology, College of Science, Chung Yuan Christian University, Chung-Li, Taoyuan City 320314, Taiwan.

Vaccines
|June 28, 2023
PubMed

Insights

Chikungunya virus (CHIKV) causes widespread outbreaks of Chikungunya fever (CHCF). This review highlights CHIKV research in India following the 2006 epidemic, aiming to advance treatments and vaccines.

Area of Science:

  • * Medical Entomology and Virology
  • * Global Public Health

Background:

  • * Chikungunya virus (CHIKV) causes Chikungunya fever (CHKF), leading to endemic and epidemic outbreaks globally.
  • * CHIKV is a significant public health threat due to its high transmission, frequent misdiagnosis, and lack of vaccines or treatments.
  • * The virus disproportionately affects resource-limited regions, including developing nations.

Purpose of the Study:

  • * To provide an overview of Chikungunya virus (CHIKV) outbreak history in India.
  • * To summarize CHIKV-related research conducted in India since the 2006 epidemic.
  • * To encourage novel research for effective treatment, prevention strategies, and vaccine development against CHIKV.

Main Methods:

  • * Comprehensive literature review of CHIKV outbreaks and research.
  • * Analysis of publications by Indian researchers and medical practitioners.
  • * Synthesis of historical data and current research trends.

Main Results:

  • * CHIKV reemerged in India in 2006, marking the most significant epidemic reported.
  • * Over 800 peer-reviewed papers on CHIKV have been published by Indian researchers since 2006.
  • * Significant research efforts in India focus on understanding CHIKV epidemiology and pathogenesis.

Conclusions:

  • * India has become a major hub for CHIKV research following the 2006 epidemic.
  • * Continued research is crucial for developing effective interventions against CHIKV infection.
  • * The review aims to stimulate high-quality research for improved CHIKV treatment and prevention strategies.
Keywords:
CHIKVbiomedical researchchikungunya researchchikungunya vaccinechikungunya virusoutbreaks

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