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A Novel Method for Angioscopic Imaging and Visualizing the Skull Base Using Complementary Metal Oxide Semiconductor
Mokshal H Porwal1,2, Christina Feller2, Justine Bales2
1Department of Neurosurgery, Allegheny General Hospital, Pittsburgh , Pennsylvania , USA.
Neurosurgery
|June 28, 2023
Summary
Complementary metal oxide semiconductor (CMOS) endoscopes show feasibility for neurointervention, enabling direct visualization of blood vessels and access to the skull base and spinal subdural space in a canine model.
Area of Science:
- Minimally invasive neurosurgery
- Medical device technology
- Endovascular neurosurgery
Background:
- Complementary metal oxide semiconductor (CMOS) electrode arrays offer novel miniaturized endoscope technology.
- The application of CMOS endoscopes in neurointervention remains unexplored.
Purpose of the Study:
- To establish the feasibility of CMOS endoscopes for neurointervention.
- To demonstrate direct visualization of the endothelial surface.
- To showcase stent and coil deployment and access to the spinal subdural space and skull base.
Main Methods:
- Utilized 3 canine models with transfemoral guide catheter insertion.
- Employed a 1.2-mm CMOS camera for endothelial inspection and device deployment visualization.
- Performed lumbar laminectomy for spinal subdural space navigation and intracranial vasculature visualization.
Main Results:
- Achieved direct visualization of the endothelial surface.
- Successfully deployed coils and stents under direct angioscopic vision.
- Demonstrated proof-of-concept for accessing the skull base and posterior cerebral vasculature via the spinal subdural space.
Conclusions:
- CMOS camera technology is feasible for direct endothelial visualization in neuroendovascular procedures.
- This technology supports common neuroendovascular procedures and skull base access.
- The study provides a proof-of-concept for CMOS endoscopes in neurointervention within a canine model.
