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Choice in Ablative Therapies for Thyroid Nodules.

Q Lina Hu1, Jennifer H Kuo1

  • 1Division of GI/Endocrine Surgery, Columbia University, New York, NY 10032, USA.

Journal of the Endocrine Society
|June 28, 2023
PubMed
Summary

Ultrasound-guided ablation is a popular alternative to surgery for thyroid nodules. This review covers thermal and nonthermal ablation techniques, including cryoablation and electroporation, for various clinical uses.

Keywords:
ethanol ablationlaser ablationmicrowave ablationradiofrequency ablationthermal ablationthyroid nodules

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Area of Science:

  • Minimally Invasive Procedures
  • Interventional Radiology
  • Oncology

Background:

  • Ultrasound-guided ablation is increasingly preferred for thyroid nodules over traditional surgery.
  • Thermal ablation is currently the most common method.
  • Nonthermal techniques like cryoablation and electroporation are emerging.

Purpose of the Study:

  • To review currently available ablative therapies for thyroid nodules.
  • To discuss the applications of these therapies in different clinical scenarios.

Main Methods:

  • Literature review of ultrasound-guided ablation techniques.
  • Analysis of thermal and nonthermal ablation methods.
  • Examination of clinical indications and outcomes.

Main Results:

  • Overview of established thermal ablation technologies.
  • Introduction to emerging nonthermal techniques (cryoablation, electroporation).
  • Discussion of suitability for various thyroid nodule types and patient conditions.

Conclusions:

  • Ultrasound-guided ablation offers advantages for thyroid nodule treatment.
  • A range of technologies, both thermal and nonthermal, are available.
  • Selection of technique depends on specific clinical indications.