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A Rare Case of Myxoid Adrenocortical Carcinoma
Carmela Claire Ferrer1, Pamela R Delos Reyes-Murillo1
1Pathology and Laboratory Medicine, National Kidney and Transplant Institute, Quezon City, PHL.
Abstract:
Myxoid adrenocortical carcinoma (myxoid ACC) is a rare subtype of adrenal cortical carcinoma with only a few cases reported in the literature. This tumor is characterized by small to large neoplastic cells in cords, diffuse sheets, or nodular architecture, which are surrounded by variable amounts of myxoid material. We are presented with an elderly female with a suprarenal mass which revealed a tumor composed of neoplastic cells surrounded by scant to abundant myxoid stroma. Expression for Melan-A, Inhibin, Synaptophysin, and Pancytokeratin, as well as a Ki-67 proliferative index of 15%, warrant a diagnosis of myxoid ACC.
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