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Area of Science:

  • Rheumatology
  • Clinical Research
  • Patient-Reported Outcomes

Background:

  • Fibromyalgia (FM) is a chronic pain syndrome with higher prevalence in females.
  • Current disease severity assessments, like the Revised Fibromyalgia Impact Questionnaire (FIQR), were validated on predominantly female samples.
  • Potential gender bias in FM assessment tools requires investigation.

Purpose of the Study:

  • To compare Revised Fibromyalgia Impact Questionnaire (FIQR) item scores between male and female fibromyalgia patients.
  • To evaluate potential gender bias in the FIQR as a fibromyalgia severity index.

Main Methods:

  • A case-control study involving 78 fibromyalgia patients (39 males, 39 females) matched for age and disease duration.
  • Patients completed an online survey including demographic data, disease variables, and the Italian version of the FIQR.
  • Univariate analysis was used to compare FIQR scores between genders.

Main Results:

  • Female fibromyalgia patients reported significantly higher total FIQR scores and physical function domain scores.
  • Females scored significantly higher on 6 out of 21 FIQR items.
  • Specifically, females scored higher on 5 out of 9 sub-items within the physical function domain.

Conclusions:

  • The Revised Fibromyalgia Impact Questionnaire (FIQR) may underestimate disease impact in male fibromyalgia patients.
  • Further research is needed to validate FM assessment tools across genders to ensure accurate severity indexing.