[Lipid metabolism in rat tissues after irradiation at doses causing interphase cell death]

Irradiation of animals with doses eliciting interphase death of 50-80% of cells activates lipogenesis and decreases the cholesterol content of cells. Cholesterol synthesis is activated after irradiation with doses causing death of 50% of cells: a further increase in radiation dose decreases the cholesterol synthesis. It is assumed that as membranes are destructed by radiation the adaptive lipogenesis activated to restore them.