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Chemotherapy-Induced Pseudocellulitis Without Prior Radiation Exposure: A Systematic Review
Leah D Kovacs1, Michaela O'Donoghue1, Anna L Cogen2
1University of Washington School of Medicine, Seattle.
Chemotherapy-induced pseudocellulitis, a reaction mimicking infection, often leads to unnecessary antibiotics and treatment delays. Further research and a clear definition are crucial for accurate diagnosis and patient care.
Area of Science:
- Oncology
- Dermatology
- Pharmacology
Background:
- Chemotherapy-induced pseudocellulitis is an under-recognized adverse cutaneous drug reaction (ACDR) that mimics infectious cellulitis.
- This condition poses diagnostic challenges and can lead to inappropriate antibiotic use and interruptions in cancer treatment.
Conclusions:
- Chemotherapy-induced ACDRs frequently mimic infectious cellulitis.
- A lack of standardized definition and research hinders accurate diagnosis and management.
- Improved understanding and diagnostic criteria are needed for better antibiotic stewardship and uninterrupted cancer care.
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