Related Experiment Video
Updated: Jul 25, 2025

Author Spotlight: Advancements in Refractive Surgical Correction for Presbyopia and Exploring Postoperative Visual Acuity
Published on: September 20, 2024
[Direct assessment of changes in biomechanical properties of the cornea after ReLEx SMILE and FemtoLASIK surgeries]
E V Boiko1,2, E S Togo1,2, A A Suetov1
1Saint Petersburg branch of S.N. Fedorov National Medical Research Center "MNTK "Eye Microsurgery", St. Petersburg, Russia.
Abstract:
The aim of this study was to evaluate corneal biomechanical properties in myopic patients after ReLEx SMILE and FemtoLASIK surgeries using the Corvis ST analyzer.
Material And Methods:
The SMILE group comprised 23 patients (46 eyes) with spherical refraction -3.8±1.8 diopters (D), the FemtoLASIK group included 18 patients (36 eyes) with spherical refraction -3.5±1.3 D. Analysis of the biomechanical properties of the cornea was carried out using the CORVIS ST device (Oculus, Germany) before and seven days after corneal refractive surgery.
Results:
In the SMILE group, with intraoperative decrease in corneal thickness of 91.43±19.43 µm, a significant increase in the following parameters was observed: deformation coefficient (DA ratio; p=0.0001), peak distance (PD; p=0.02) and inverse concave radius (ICR; p=0.003); a decrease in the stiffness parameter at first applanation (SP-A1; p=0.0001), Corvis biomechanical index (CBI; p=0.0001), intraocular pressure (IOP; p=0.001). In the FemtoLASIK group, with intraoperative decrease in corneal thickness of 75.33±32.3 µm, we observed a significant increase in DA ratio (p=0.0002), PD (p=0.04), ICR (p=0.0002), a decrease in SP-A1 (p<0.0001), IOP values (p=0.0003). In comparison with the FemtoLASIK group, the deformation amplitude DA changed significantly less in the SMILE group (p=0.04). In the FemtoLASIK group, in comparison with the SMILE group, the DA ratio (p=0.0009) and SP-A1 (p=0.0003) significantly increased. Intraoperative corneal thickness change correlates with ICR both in SMILE (R=0.52) and in FemtoLASIK (R=0.65).
Conclusion:
Corneal biomechanical properties determined with CORVIS ST in eyes with mild to moderate myopia change to a lesser extent after ReLEx SMILE compared to FemtoLASIK.

