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Improvement in Intraoperative Image Quality in Transcranial Magnetic Resonance-Guided Focused Ultrasound Surgery
Hiroki Hori1, Yusuke Yamada2, Masayuki Nakano3
1Department of FUS Center, Moriyama Neurosurgical Center Hospital, Tokyo, Japan.
Stereotactic and Functional Neurosurgery
|June 28, 2023
Summary
Manual transmitter gain (TG) significantly improves intraoperative image quality for transcranial magnetic resonance-guided focused ultrasound surgery (TcMRgFUS). This enhancement allows for clearer visualization and more precise targeting of lesions during the procedure.
Area of Science:
- Neurosurgery
- Medical Imaging
- Ultrasound Technology
Background:
- Transcranial magnetic resonance-guided focused ultrasound surgery (TcMRgFUS) relies on intraoperative MRI for lesion visualization and adjustment.
- Current 3.0T MRI systems provide insufficient image quality for precise lesion detection during TcMRgFUS.
- Image quality is influenced by transmitter gain (TG) settings.
Purpose of the Study:
- To develop and validate a method for improving intraoperative MRI image quality during TcMRgFUS.
- To compare the effectiveness of manually adjusted TG versus automatically adjusted TG (auto TG) for enhancing image quality.
Main Methods:
- Acquired T2-weighted images (T2WIs) using both auto TG and manual TG on a 3.0T MRI system.
- Evaluated phantom images for actual flip angle (FA), image uniformity, and signal-to-noise ratio (SNR).
- Assessed intraoperative T2WIs from 5 TcMRgFUS patients, retrospectively estimating lesion contrast-to-noise ratio (CNR).
Main Results:
- Manual TG showed no variation in FA, unlike auto TG (p < 0.01).
- Manual TG resulted in more uniform images and significantly higher SNRs compared to auto TG (p < 0.01).
- Intraoperative images with manual TG clearly delineated lesions, showing considerably higher CNR than auto TG images (p < 0.01).
Conclusions:
- Manual TG improves intraoperative T2WIs quality during TcMRgFUS on a 3.0T MRI system.
- This method enhances lesion delineation compared to the current auto TG approach.
- Improved image quality facilitates more precise adjustments in TcMRgFUS procedures.
Keywords:
Essential tremorFlip angle, magnetic resonance imagingStereotactic thalamotomyTranscranial magnetic resonance-guided focused ultrasound surgeryTransmitter gain
