[Granulomatous and allergic angiitis (Churg and Strauss). A case report (author's transl)]

The autopsy findings in a case of granulomatous and allergic angiitis, or Chung and Strauss' disease, are reported. Certain uncommon peculiarities were seen during the course of the disease, such as the presence of multiple lymph nodes presumed from a clinical standpoint to be lymphomas. Its differential diagnosis from other forms of granulomatous vasculitis, especially from those which affect the lungs preferentially or exclusively, is discussed. Special consideration is given to the limited forms of Wegener's disease, which is surprisingly similar morphologically; its more significant differences lie in the clinical and topographic areas, rather than in morphology. The lymph nodes, presumed to be lymphomas from a clinical view-point, are a truly exceptional circumstances in this disease. In the author's opinion the histologic pattern clearly indicates that the etiopathogenesis lies in a congenital or acquired immune disturbance. The recent literature is review, while the present knowledge about the broad and confusing spectrum of these conditions --arteritis, and pulmonary granulomatosis-- is discussed.