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Medication safety in chronic kidney disease
1Department of Family Medicine and Community Health, Division of Health System Sciences, UMass Chan Medical School, Worcester, Massachusetts, USA.
Current Opinion in Nephrology and Hypertension
|June 29, 2023
Summary
Certain medications worsen chronic kidney disease (CKD) and cause kidney damage. Careful drug selection and dose adjustments are crucial for patients with CKD to avoid drug-induced harm and kidney injury.
Area of Science:
- Nephrology
- Pharmacology
- Internal Medicine
Background:
- Drug-induced nephrotoxicity and accelerated chronic kidney disease (CKD) progression are significant clinical concerns.
- Identifying medications that pose risks to kidney function in CKD patients is essential for patient safety.
Conclusions:
- Numerous medications can elevate the risk of acute kidney injury or CKD progression.
- Judicious medication management, including dose optimization and selection of safer alternatives, is vital to mitigate drug-induced harm in CKD patients.
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