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Updated: Jul 25, 2025

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
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Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants

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Changes and predictors of maternal depressive and anxiety symptoms during the COVID-19 pandemic

Nicole Racine1, André Plamondon2, Brae Anne McArthur3,4

  • 1School of Psychology, University of Ottawa, 136 Jean-Jacques Lussier, Vanier 4087, Ottawa, Ontario, K1N 6N5, Canada. nracine2@uottawa.ca.

Archives of Women'S Mental Health
|June 29, 2023
PubMed

Longitudinal changes in maternal depressive and anxiety symptoms and predictors of symptom variation among a group of middle-to-upper income Canadian women (n = 2152) were examined prior to the pandemic (2017-2019) and at three pandemic timepoints (May-July 2020, March-April 2021, November-December 2021). Mean maternal depression and anxiety scores were elevated throughout the pandemic. Pre-pandemic depressive symptoms were associated with greater increases in depressive symptoms. Coping and relationship quality were protective factors. Supporting the development of coping strategies may mitigate mental health concerns among mothers.

Keywords:
AnxietyCOVID-19DepressionMaternal mental health

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