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Published on: November 9, 2017
Immune-mediated necrotizing myopathy: Report of two cases
Bi-Hong Chen1, Xue-Min Zhu2, Lei Xie2
1Department of Clinical Medicine, Weifang Medical University, Weifang 261053, Shandong Province, China.
Background:
Immune-mediated necrotizing myopathy is a rare autoimmune myopathy characterized by muscle weakness and elevated serum creatine kinase, with unique skeletal muscle pathology and magnetic resonance imaging features.
Case Summary:
In this paper, two patients are reported: One was positive for anti-signal recognition particle antibody, and the other was positive for anti-3-hydroxy-3-methylglutaryl coenzyme A reductase antibody.
Conclusion:
The clinical characteristics and treatment of the two patients were analysed, and the literature was reviewed to improve the recognition, diagnosis, and treatment of this disease.
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